6V3Y

Crystal structure of EED in complex with PALI1-K1219me3 peptide

Summary for 6V3Y

Entry DOI	10.2210/pdb6v3y/pdb
Descriptor	Polycomb protein EED, PALI1 peptide (3 entities in total)
Functional Keywords	eed, pali1, tri-methyl-lysine, lcor, c10orf12, gene regulation
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	42039.80
Authors	Zhang, Q.,Davidovich, C. (deposition date: 2019-11-26, release date: 2021-05-26, Last modification date: 2023-10-11)
Primary citation	Zhang, Q.,Agius, S.C.,Flanigan, S.F.,Uckelmann, M.,Levina, V.,Owen, B.M.,Davidovich, C. PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis. Nat Commun, 12:4592-4592, 2021 Cited by PubMed: 34321472 DOI: 10.1038/s41467-021-24866-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.63 Å)

Structure validation