6V3X
Crystal structure of EED in complex with PALI1-K1241me3 peptide
Summary for 6V3X
Entry DOI | 10.2210/pdb6v3x/pdb |
Descriptor | Polycomb protein EED, PALI1 peptide (3 entities in total) |
Functional Keywords | eed, pali1, lcor, c10orf12, tri-methyl-lysine, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 43089.20 |
Authors | Zhang, Q.,Davidovich, C. (deposition date: 2019-11-26, release date: 2021-05-26, Last modification date: 2023-10-11) |
Primary citation | Zhang, Q.,Agius, S.C.,Flanigan, S.F.,Uckelmann, M.,Levina, V.,Owen, B.M.,Davidovich, C. PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis. Nat Commun, 12:4592-4592, 2021 Cited by PubMed: 34321472DOI: 10.1038/s41467-021-24866-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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