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Crystal structure of human peptidylarginine deiminase type4 (PAD4) in complex with benzoyl-L-arginine amide
分子名称:	CALCIUM ION, N-[(E)-2-AMINO-1-(3-{[AMINO(IMINO)METHYL]AMINO}PROPYL)-2-HYDROXYVINYL]BENZAMIDE, Protein-arginine deiminase type IV, ...
著者	Arita, K, Hashimoto, H, Shimizu, T, Nakashima, K, Yamada, M, Sato, M.
登録日	2004-05-12
公開日	2004-07-13
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural basis for Ca(2+)-induced activation of human PAD4 Nat.Struct.Mol.Biol., 11, 2004

1WD9

Calcium bound form of human peptidylarginine deiminase type4 (PAD4)
分子名称:	CALCIUM ION, Protein-arginine deiminase type IV, SULFATE ION
著者	Arita, K, Hashimoto, H, Shimizu, T, Nakashima, K, Yamada, M, Sato, M.
登録日	2004-05-12
公開日	2004-07-13
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Structural basis for Ca(2+)-induced activation of human PAD4 Nat.Struct.Mol.Biol., 11, 2004

1WD8

Calcium free form of human peptidylarginine deiminase type4 (PAD4)
分子名称:	Protein-arginine deiminase type IV
著者	Arita, K, Hashimoto, H, Shimizu, T, Nakashima, K, Yamada, M, Sato, M.
登録日	2004-05-12
公開日	2004-07-13
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structural basis for Ca(2+)-induced activation of human PAD4 Nat.Struct.Mol.Biol., 11, 2004

2E1N

Crystal structure of the Cyanobacterium circadian clock modifier Pex
分子名称:	Pex, SULFATE ION
著者	Arita, K, Shimizu, T.
登録日	2006-10-26
公開日	2006-11-28
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural and Biochemical Characterization of a Cyanobacterium Circadian Clock-modifier Protein J.Biol.Chem., 282, 2007

3ASK

Structure of UHRF1 in complex with histone tail
分子名称:	E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION
著者	Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M.
登録日	2010-12-16
公開日	2012-01-25
最終更新日	2013-06-05
実験手法	X-RAY DIFFRACTION (2.904 Å)
主引用文献	Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012

3ASL

Structure of UHRF1 in complex with histone tail
分子名称:	1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ...
著者	Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M.
登録日	2010-12-16
公開日	2012-01-25
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.41 Å)
主引用文献	Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109, 2012

2DEW

Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal tail including Arg8
分子名称:	10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ...
著者	Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
登録日	2006-02-18
公開日	2006-04-11
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006

2DEX

Crystal structure of human peptidylarginine deiminase 4 in complex with histone H3 N-terminal peptide including Arg17
分子名称:	10-mer peptide from histone H3, CALCIUM ION, Protein-arginine deiminase type IV, ...
著者	Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
登録日	2006-02-18
公開日	2006-04-11
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006

2DEY

Crystal structure of human peptidylarginine deiminase 4 in complex with histone H4 N-terminal tail including Arg3
分子名称:	10-mer peptide from histone H4, CALCIUM ION, Protein-arginine deiminase type IV, ...
著者	Arita, K, Shimizu, T, Hashimoto, H, Hidaka, Y, Yamada, M, Sato, M.
登録日	2006-02-18
公開日	2006-04-11
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4 Proc.Natl.Acad.Sci.Usa, 103, 2006

2ZKE

Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
分子名称:	DNA (5'-D(DCPDTPDAPDCPDCPDGPDGPDAPDTPDTPDGPDC)-3'), DNA (5'-D(DGPDCPDAPDAPDTPDCP(5CM)PDGPDGPDTPDAPDG)-3'), E3 ubiquitin-protein ligase UHRF1
著者	Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
登録日	2008-03-19
公開日	2008-09-09
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008

2ZKG

Crystal structure of unliganded SRA domain of mouse Np95
分子名称:	1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1
著者	Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
登録日	2008-03-19
公開日	2008-09-09
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (1.77 Å)
主引用文献	Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008

2ZKD

Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
分子名称:	1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(DCPDTPDAPDCPDCPDGPDGPDAPDTPDTPDGPDC)-3'), ...
著者	Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
登録日	2008-03-19
公開日	2008-09-09
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (1.6 Å)
主引用文献	Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008

2ZKF

Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
分子名称:	DNA (5'-D(DCPDTPDAPDTPDCP(5CM)PDGPDGPDTPDGPDA)-3'), DNA (5'-D(PDCPDAPDCPDCPDGPDGPDAPDTPDAPDGPDA)-3'), E3 ubiquitin-protein ligase UHRF1
著者	Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
登録日	2008-03-19
公開日	2008-09-09
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008

6IIW

Crystal structure of human UHRF1 PHD finger in complex with PAF15
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase UHRF1, PCNA-associated factor, ...
著者	Arita, K, Kori, S.
登録日	2018-10-07
公開日	2019-10-09
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.699 Å)
主引用文献	Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nat Commun, 11, 2020

2RRU

Solution structure of the UBA omain of p62 and its interaction with ubiquitin
分子名称:	Sequestosome-1
著者	Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H.
登録日	2011-06-09
公開日	2011-06-29
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Crystal structure of the UBA omain of p62 and its interaction with ubiquitin To be Published

7FB7

Crystal structure of human UHRF1 TTD in complex with 5-amino-2,4-dimethylpyridine
分子名称:	(4S)-2-METHYL-2,4-PENTANEDIOL, 5-amino-2,4-dimethylpyridine, DIMETHYL SULFOXIDE, ...
著者	Kori, S, Arita, K, Yoshimi, S.
登録日	2021-07-08
公開日	2022-01-05
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (1.45 Å)
主引用文献	Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1. Bioorg.Med.Chem., 52, 2021

5WVO

Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3
分子名称:	DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ...
著者	Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K.
登録日	2016-12-28
公開日	2017-11-15
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.997 Å)
主引用文献	Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance Mol. Cell, 68, 2017

7XGA

NMR strucutre of chimeric protein for model of PHD-Stella complex
分子名称:	Chimera of E3 ubiquitin-protein ligase UHRF1 and Developmental pluripotency-associated protein 3, ZINC ION
著者	Kobayashi, N, Konuma, T, Arita, K.
登録日	2022-04-04
公開日	2022-12-07
最終更新日	2024-05-15
実験手法	SOLUTION NMR
主引用文献	Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger. Nucleic Acids Res., 50, 2022

7XI9

Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated H3 and hemimethylated DNA analog (CXXC-ordered form)
分子名称:	DNA (5'-D(APCPTPTPAP(5CM)PGPGPAPAPGPG)-3'), DNA (5'-D(CPCPTPTPCP(C55)PGPTPAPAPGPT)-3'), DNA (cytosine-5)-methyltransferase 1, ...
著者	Onoda, H, Kikuchi, A, Kori, S, Yoshimi, S, Yamagata, A, Arita, K.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (2.52 Å)
主引用文献	Structural basis for activation of DNMT1. Nat Commun, 13, 2022

7XIB

Cryo-EM structure of human DNMT1 (aa:351-1616) in complex with ubiquitinated H3 and hemimethylated DNA analog (CXXC-disordered form)
分子名称:	DNA (5'-D(APCPTPTPAP(5CM)PGPGPAPAPGPG)-3'), DNA (5'-D(CPCPTPTPCP(C55)PGPTPAPAPGPT)-3'), DNA (cytosine-5)-methyltransferase 1, ...
著者	Onoda, H, Kikuchi, A, Kori, S, Yoshimi, S, Yamagata, A, Arita, K.
登録日	2022-04-12
公開日	2022-11-30
最終更新日	2022-12-07
実験手法	ELECTRON MICROSCOPY (2.23 Å)
主引用文献	Structural basis for activation of DNMT1. Nat Commun, 13, 2022

5YY9

Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3
分子名称:	E3 ubiquitin-protein ligase UHRF1, Ligase 1
著者	Kori, S, Defossez, P.A, Arita, K.
登録日	2017-12-08
公開日	2018-12-12
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.653 Å)
主引用文献	Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation. Structure, 27, 2019

5YYA

Crystal structure of Tandem Tudor Domain of human UHRF1
分子名称:	1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1, SULFATE ION
著者	Kori, S, Defossez, P.A, Arita, K.
登録日	2017-12-08
公開日	2018-12-12
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.7 Å)
主引用文献	Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation. Structure, 27, 2019

6K3A

Crystal structure of human PCNA in complex with DNMT1 PIP box motif.
分子名称:	Peptide from DNA (cytosine-5)-methyltransferase 1, Proliferating cell nuclear antigen
著者	Jimenji, T, Kori, S, Arita, K.
登録日	2019-05-17
公開日	2019-06-26
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structure of PCNA in complex with DNMT1 PIP box reveals the basis for the molecular mechanism of the interaction. Biochem.Biophys.Res.Commun., 516, 2019

2CT9

The crystal structure of calcineurin B homologous proein 1 (CHP1)
分子名称:	CALCIUM ION, Calcium-binding protein p22
著者	Naoe, Y, Arita, K, Hashimoto, H, Kanazawa, H, Sato, M, Shimizu, T.
登録日	2005-05-23
公開日	2005-07-05
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural characterization of calcineurin B homologous protein 1 J.Biol.Chem., 280, 2005

2DW5

Crystal structure of human peptidylarginine deiminase 4 in complex with N-alpha-benzoyl-N5-(2-fluoro-1-iminoethyl)-L-ornithine amide
分子名称:	CALCIUM ION, N-[(1S)-1-(AMINOCARBONYL)-4-(ETHANIMIDOYLAMINO)BUTYL]BENZAMIDE, Protein-arginine deiminase type-4, ...
著者	Luo, Y, Arita, K, Sato, M, Thompson, P.R.
登録日	2006-08-04
公開日	2006-10-17
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization Biochemistry, 45, 2006

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表示件数:	25
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