6IIW
Crystal structure of human UHRF1 PHD finger in complex with PAF15
Summary for 6IIW
Entry DOI | 10.2210/pdb6iiw/pdb |
Descriptor | E3 ubiquitin-protein ligase UHRF1, PCNA-associated factor, ZINC ION, ... (5 entities in total) |
Functional Keywords | dna methylation, histone modification, replication, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 9532.23 |
Authors | |
Primary citation | Nishiyama, A.,Mulholland, C.B.,Bultmann, S.,Kori, S.,Endo, A.,Saeki, Y.,Qin, W.,Trummer, C.,Chiba, Y.,Yokoyama, H.,Kumamoto, S.,Kawakami, T.,Hojo, H.,Nagae, G.,Aburatani, H.,Tanaka, K.,Arita, K.,Leonhardt, H.,Nakanishi, M. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nat Commun, 11:1222-1222, 2020 Cited by PubMed: 32144273DOI: 10.1038/s41467-020-15006-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.699 Å) |
Structure validation
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