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6IIW

Crystal structure of human UHRF1 PHD finger in complex with PAF15

Summary for 6IIW
Entry DOI10.2210/pdb6iiw/pdb
DescriptorE3 ubiquitin-protein ligase UHRF1, PCNA-associated factor, ZINC ION, ... (5 entities in total)
Functional Keywordsdna methylation, histone modification, replication, ligase
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight9532.23
Authors
Arita, K.,Kori, S. (deposition date: 2018-10-07, release date: 2019-10-09, Last modification date: 2023-11-22)
Primary citationNishiyama, A.,Mulholland, C.B.,Bultmann, S.,Kori, S.,Endo, A.,Saeki, Y.,Qin, W.,Trummer, C.,Chiba, Y.,Yokoyama, H.,Kumamoto, S.,Kawakami, T.,Hojo, H.,Nagae, G.,Aburatani, H.,Tanaka, K.,Arita, K.,Leonhardt, H.,Nakanishi, M.
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation.
Nat Commun, 11:1222-1222, 2020
Cited by
PubMed: 32144273
DOI: 10.1038/s41467-020-15006-4
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.699 Å)
Structure validation

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