3ASL

Structure of UHRF1 in complex with histone tail

Summary for 3ASL

Entry DOI	10.2210/pdb3asl/pdb
Related	2FAZ 2ZKD 2ZO0 3ASK 3CLZ 3DB3 3FL2
Descriptor	E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION, ... (5 entities in total)
Functional Keywords	histone reader module, epigenetic regulation, histone h3, ligase-dna binding protein complex, ligase/dna binding protein
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q96T88 P84243
Total number of polymer chains	2
Total formula weight	9682.32
Authors	Arita, K.,Sugita, K.,Unoki, M.,Hamamoto, R.,Sekiyama, N.,Tochio, H.,Ariyoshi, M.,Shirakawa, M. (deposition date: 2010-12-16, release date: 2012-01-25, Last modification date: 2024-03-13)
Primary citation	Arita, K.,Isogai, S.,Oda, T.,Unoki, M.,Sugita, K.,Sekiyama, N.,Kuwata, K.,Hamamoto, R.,Tochio, H.,Sato, M.,Ariyoshi, M.,Shirakawa, M. Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1 Proc.Natl.Acad.Sci.USA, 109:12950-12955, 2012 Cited by PubMed: 22837395 DOI: 10.1073/pnas.1203701109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.41 Å)

Structure validation