2ZKG

Crystal structure of unliganded SRA domain of mouse Np95

Summary for 2ZKG

Entry DOI	10.2210/pdb2zkg/pdb
Related	2ZKD 2ZKE 2ZKF
Descriptor	E3 ubiquitin-protein ligase UHRF1, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	protein-dna interaction, cell cycle, developmental protein, dna damage, dna repair, dna-binding, ligase, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation pathway, zinc-finger
Biological source	Mus musculus (Mouse)
Cellular location	Nucleus: Q8VDF2
Total number of polymer chains	4
Total formula weight	93876.71
Authors	Arita, K.,Ariyoshi, M.,Tochio, H.,Nakamura, Y.,Shirakawa, M. (deposition date: 2008-03-19, release date: 2008-09-09, Last modification date: 2023-11-01)
Primary citation	Arita, K.,Ariyoshi, M.,Tochio, H.,Nakamura, Y.,Shirakawa, M. Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455:818-821, 2008 Cited by PubMed: 18772891 DOI: 10.1038/nature07249 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.77 Å)

Structure validation