5YY9

Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3

Summary for 5YY9

Entry DOI	10.2210/pdb5yy9/pdb
Descriptor	E3 ubiquitin-protein ligase UHRF1, Ligase 1 (3 entities in total)
Functional Keywords	maintenance of dna methylation, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	39604.56
Authors	Kori, S.,Defossez, P.A.,Arita, K. (deposition date: 2017-12-08, release date: 2018-12-12, Last modification date: 2023-11-22)
Primary citation	Kori, S.,Ferry, L.,Matano, S.,Jimenji, T.,Kodera, N.,Tsusaka, T.,Matsumura, R.,Oda, T.,Sato, M.,Dohmae, N.,Ando, T.,Shinkai, Y.,Defossez, P.A.,Arita, K. Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation. Structure, 27:485-, 2019 Cited by PubMed: 30639225 DOI: 10.1016/j.str.2018.11.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.653 Å)

Structure validation