5YY9
Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | E3 ubiquitin-protein ligase UHRF1 | polymer | 154 | 18162.2 | 2 | UniProt (Q96T88) Pfam (PF12148) | Homo sapiens (Human) | Inverted CCAAT box-binding protein of 90 kDa,Nuclear protein 95,Nuclear zinc finger protein Np95,hNp95,RING finger protein 106,RING-type E3 ubiquitin transferase UHRF1,Transcription factor ICBP90,Ubiquitin-like PHD and RING finger domain-containing protein 1,hUHRF1,Ubiquitin-like-containing PHD and RING finger domains protein 1 |
| 2 | C, D (C, D) | Ligase 1 | polymer | 13 | 1640.1 | 2 | UniProt (by SIFTS) (P18858) | synthetic construct | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
A, B: 123 - 285 (UniProt: Q96T88)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 167 | deletion |
| - | Arg 168 | deletion |
| - | Asp 169 | deletion |
| - | Glu 170 | deletion |
| - | Pro 171 | deletion |
| - | Cys 172 | deletion |
| - | Ser 173 | deletion |
| - | Ser 174 | deletion |
| - | Thr 175 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 39604.6 | |
| All* | Total formula weight | 39604.6 |
