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2B0U
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The Structure of the Follistatin:Activin Complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Follistatin, IRIDIUM (III) ION, ...
著者Thompson, T.B, Lerch, T.F, Cook, R.W, Woodruff, T.K, Jardetzky, T.S.
登録日2005-09-14
公開日2005-10-11
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Follistatin:Activin Complex Reveals Antagonism of Both Type I and Type II Receptor Binding.
Dev.Cell, 9, 2005
1C9K
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THE THREE DIMENSIONAL STRUCTURE OF ADENOSYLCOBINAMIDE KINASE/ ADENOSYLCOBINAMIDE PHOSPHATE GUALYLYLTRANSFERASE (COBU) COMPLEXED WITH GMP: EVIDENCE FOR A SUBSTRATE INDUCED TRANSFERASE ACTIVE SITE
分子名称: ADENOSYLCOBINAMIDE KINASE, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
著者Thompson, T.B, Thomas, M.G, Esclante-Semerena, J.C, Rayment, I.
登録日1999-08-02
公開日1999-08-18
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase (CobU) complexed with GMP: evidence for a substrate-induced transferase active site.
Biochemistry, 38, 1999
1CBU
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ADENOSYLCOBINAMIDE KINASE/ADENOSYLCOBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE (COBU) FROM SALMONELLA TYPHIMURIUM
分子名称: ADENOSYLCOBINAMIDE KINASE/ADENOSYLCOBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE, SULFATE ION
著者Thompson, T.B, Thomas, M.G, Escalante-Semerena, J.C, Rayment, I.
登録日1998-03-12
公開日1998-12-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Three-dimensional structure of adenosylcobinamide kinase/adenosylcobinamide phosphate guanylyltransferase from Salmonella typhimurium determined to 2.3 A resolution,.
Biochemistry, 37, 1998
1TUW
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BU of 1tuw by Molmil
Structural and Functional Analysis of Tetracenomycin F2 Cyclase from Streptomyces glaucescens: A Type-II Polyketide Cyclase
分子名称: SULFATE ION, Tetracenomycin polyketide synthesis protein tcmI
著者Thompson, T.B, Katayama, K, Watanabe, K, Hutchinson, C.R, Rayment, I.
登録日2004-06-25
公開日2004-08-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and functional analysis of tetracenomycin F2 cyclase from Streptomyces glaucescens. A type II polyketide cyclase.
J.Biol.Chem., 279, 2004
1NYU
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Crystal Structure of Activin A Bound to the ECD of ActRIIB
分子名称: Inhibin beta A chain, activin receptor
著者Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
登録日2003-02-13
公開日2003-04-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
1NYS
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Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
分子名称: Inhibin beta A chain, activin receptor
著者Thompson, T.B, Woodruff, T.K, Jardetzky, T.S.
登録日2003-02-13
公開日2003-04-08
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions
EMBO J., 22, 2003
4X1J
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X-ray crystal structure of the dimeric BMP antagonist NBL1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroblastoma suppressor of tumorigenicity 1
著者Thompson, T.B, Nolan, K, Kattamuri, C.
登録日2014-11-24
公開日2015-01-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Neuroblastoma Suppressor of Tumorigenicity 1 (NBL1): INSIGHTS FOR THE FUNCTIONAL VARIABILITY ACROSS BONE MORPHOGENETIC PROTEIN (BMP) ANTAGONISTS.
J.Biol.Chem., 290, 2015
1FHU
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CRYSTAL STRUCTURE ANALYSIS OF O-SUCCINYLBENZOATE SYNTHASE FROM E. COLI
分子名称: O-SUCCINYLBENZOATE SYNTHASE
著者Rayment, I, Thompson, T.B, Gerlt, J.A.
登録日2000-08-02
公開日2000-08-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Evolution of enzymatic activity in the enolase superfamily: structure of o-succinylbenzoate synthase from Escherichia coli in complex with Mg2+ and o-succinylbenzoate.
Biochemistry, 39, 2000
1FHV
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CRYSTAL STRUCTURE ANALYSIS OF O-SUCCINYLBENZOATE SYNTHASE FROM E. COLI COMPLEXED WITH MG AND OSB
分子名称: 2-SUCCINYLBENZOATE, MAGNESIUM ION, O-SUCCINYLBENZOATE SYNTHASE
著者Rayment, I, Thompson, T.B, Gerlt, J.A.
登録日2000-08-02
公開日2000-08-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Evolution of enzymatic activity in the enolase superfamily: structure of o-succinylbenzoate synthase from Escherichia coli in complex with Mg2+ and o-succinylbenzoate.
Biochemistry, 39, 2000
3B4V
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X-Ray structure of Activin in complex with FSTL3
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Inhibin beta A chain, ...
著者Thompson, T.B.
登録日2007-10-24
公開日2008-09-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.
J.Biol.Chem., 283, 2008
5JHW
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BU of 5jhw by Molmil
Crystal Structure of the GDF11:Follistatin 288 complex
分子名称: CITRATE ANION, Follistatin, Growth/differentiation factor 11, ...
著者Walker, R.G, Thompson, T.B.
登録日2016-04-21
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
5JI1
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BU of 5ji1 by Molmil
Crystal Structure of GDF8
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Growth/differentiation factor 8
著者Walker, R.G, Thompson, T.B.
登録日2016-04-21
公開日2017-03-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for potency differences between GDF8 and GDF11.
BMC Biol., 15, 2017
5HK5
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BU of 5hk5 by Molmil
Structure of the Grem2-GDF5 Inhibitory Complex
分子名称: Gremlin-2, Growth/differentiation factor 5
著者Nolan, K, Thompson, T.B, Read, R.J.
登録日2016-01-13
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of Gremlin-2 in Complex with GDF5 Gives Insight into DAN-Family-Mediated BMP Antagonism.
Cell Rep, 16, 2016
7MRZ
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Structure of GDF11 bound to fused ActRIIB-ECD and Alk4-ECD with Anti-ActRIIB Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B,Activin receptor type-1B, Fab Heavy Chain, ...
著者Goebel, E.J, Kattamuri, C, Gipson, G.R, Thompson, T.B.
登録日2021-05-10
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of activin ligand traps using natural sets of type I and type II TGF beta receptors.
Iscience, 25, 2022
6MAC
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BU of 6mac by Molmil
Ternary structure of GDF11 bound to ActRIIB-ECD and Alk5-ECD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 11, ...
著者Goebel, E.J, Thompson, T.B.
登録日2018-08-27
公開日2019-07-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
8E3G
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BMP2/GDF5 heterodimer
分子名称: Bone morphogenetic protein 2, GLYCEROL, Growth/differentiation factor 5
著者Gipson, G.R, Nolan, K.T, Thompson, T.B.
登録日2022-08-17
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers.
Bmc Biol., 21, 2023
4JPH
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BU of 4jph by Molmil
Crystal structure of Protein Related to DAN and Cerberus (PRDC)
分子名称: CITRIC ACID, GLUTATHIONE, GLYCEROL, ...
著者Deng, X, Nolan, K.T, Kattamuri, C, Thompson, T.B.
登録日2013-03-19
公開日2013-07-24
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structure of protein related to dan and cerberus: insights into the mechanism of bone morphogenetic protein antagonism.
Structure, 21, 2013
3SEK
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BU of 3sek by Molmil
Crystal Structure of the Myostatin:Follistatin-like 3 Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Follistatin-related protein 3, Growth/differentiation factor 8
著者Cash, J.N, Thompson, T.B.
登録日2011-06-10
公開日2011-11-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.401 Å)
主引用文献Structure of myostatinfollistatin-like 3: N-terminal domains of follistatin-type molecules exhibit alternate modes of binding.
J.Biol.Chem., 287, 2012
3S84
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Dimeric apoA-IV
分子名称: Apolipoprotein A-IV, SULFATE ION
著者Deng, X, Davidson, W.S, Thompson, T.B.
登録日2011-05-27
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-Association.
Structure, 20, 2012
1Z4X
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand Sialyllactose (soaked with Sialyllactose, pH8.0)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4V
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH 7.0)
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Z
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA(soaked with sialic acid, pH7.0))
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4W
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with DANA, pH8.0)
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z50
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) with ligand DANA (soaked with sialic acid, pH 8.0)
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005
1Z4Y
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Parainfluenza Virus 5 (SV5) Hemagglutinin-Neuraminidase (HN) (pH 8.0)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Yuan, P, Thompson, T.B, Wurzburg, B.A, Paterson, R.G, Lamb, R.A, Jardetzky, T.S.
登録日2005-03-16
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose.
Structure, 13, 2005

 

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