4X1J

X-ray crystal structure of the dimeric BMP antagonist NBL1

Summary for 4X1J

• Entry DOI: 10.2210/pdb4x1j/pdb
• Related: 4JPH
• Descriptor: Neuroblastoma suppressor of tumorigenicity 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: bmp antagonist, dan family, cystine-knot, bmp binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 25749.35

Authors

Thompson, T.B.,Nolan, K.,Kattamuri, C. (deposition date: 2014-11-24, release date: 2015-01-14, Last modification date: 2020-07-29)

• Primary citation: Nolan, K.,Kattamuri, C.,Luedeke, D.M.,Angerman, E.B.,Rankin, S.A.,Stevens, M.L.,Zorn, A.M.,Thompson, T.B.; Structure of Neuroblastoma Suppressor of Tumorigenicity 1 (NBL1): INSIGHTS FOR THE FUNCTIONAL VARIABILITY ACROSS BONE MORPHOGENETIC PROTEIN (BMP) ANTAGONISTS.; J.Biol.Chem., 290:4759-4771, 2015; PubMed: 25561725; DOI: 10.1074/jbc.M114.628412

Experimental method

X-RAY DIFFRACTION (2.5 Å)