4JPH

Crystal structure of Protein Related to DAN and Cerberus (PRDC)

Summary for 4JPH

Entry DOI	10.2210/pdb4jph/pdb
Descriptor	Gremlin-2, GLYCEROL, GLUTATHIONE, ... (5 entities in total)
Functional Keywords	cystine knot, dan domain, can domain, bmp antagonist, bmp-2, bmp-4, bmp-7, gdf-5, gsh, extracellular, cytokine
Biological source	Mus musculus (mouse)
Cellular location	Secreted : O88273
Total number of polymer chains	4
Total formula weight	71273.38
Authors	Deng, X.,Nolan, K.T.,Kattamuri, C.,Thompson, T.B. (deposition date: 2013-03-19, release date: 2013-07-24, Last modification date: 2017-11-15)
Primary citation	Nolan, K.,Kattamuri, C.,Luedeke, D.M.,Deng, X.,Jagpal, A.,Zhang, F.,Linhardt, R.J.,Kenny, A.P.,Zorn, A.M.,Thompson, T.B. Structure of protein related to dan and cerberus: insights into the mechanism of bone morphogenetic protein antagonism. Structure, 21:1417-1429, 2013 Cited by PubMed: 23850456 DOI: 10.1016/j.str.2013.06.005 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation