7D3B
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![BU of 7d3b by Molmil](/molmil-images/mine/7d3b) | flavone reductase | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, Cd1, FLAVIN MONONUCLEOTIDE | 著者 | Hong, S, Yang, G.H, Zhang, P. | 登録日 | 2020-09-18 | 公開日 | 2021-03-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Discovery of an ene-reductase for initiating flavone and flavonol catabolism in gut bacteria. Nat Commun, 12, 2021
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7D3A
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![BU of 7d3a by Molmil](/molmil-images/mine/7d3a) | flavone reductase | 分子名称: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Cd1, FLAVIN MONONUCLEOTIDE | 著者 | Hong, S, Yang, G.H, Zhang, P. | 登録日 | 2020-09-18 | 公開日 | 2021-03-03 | 最終更新日 | 2021-09-29 | 実験手法 | X-RAY DIFFRACTION (2.552 Å) | 主引用文献 | Discovery of an ene-reductase for initiating flavone and flavonol catabolism in gut bacteria. Nat Commun, 12, 2021
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6BYR
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![BU of 6byr by Molmil](/molmil-images/mine/6byr) | Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PKAc alpha | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha chimera, MAGNESIUM ION, ... | 著者 | Cao, B, Lu, T.W, Martinez Fiesco, J.A, Tomasini, M, Fan, L, Simon, S.M, Taylor, S.S, Zhang, P. | 登録日 | 2017-12-21 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.661 Å) | 主引用文献 | Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha. Structure, 27, 2019
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4PBV
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![BU of 4pbv by Molmil](/molmil-images/mine/4pbv) | Crystal structure of chicken receptor protein tyrosine phosphatase sigma in complex with TrkC | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NT-3 growth factor receptor, Protein-tyrosine phosphatase CRYPalpha1 isoform, ... | 著者 | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | 登録日 | 2014-04-14 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis. Nat Commun, 5, 2014
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4PBX
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![BU of 4pbx by Molmil](/molmil-images/mine/4pbx) | Crystal structure of the six N-terminal domains of human receptor protein tyrosine phosphatase sigma | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase S | 著者 | Coles, C.H, Mitakidis, N, Zhang, P, Elegheert, J, Lu, W, Stoker, A.W, Nakagawa, T, Craig, A.M, Jones, E.Y, Aricescu, A.R. | 登録日 | 2014-04-14 | 公開日 | 2014-11-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Structural basis for extracellular cis and trans RPTP sigma signal competition in synaptogenesis. Nat Commun, 5, 2014
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1XRT
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![BU of 1xrt by Molmil](/molmil-images/mine/1xrt) | The Crystal Structure of a Novel, Latent Dihydroorotase from Aquifex Aeolicus at 1.7 A Resolution | 分子名称: | Dihydroorotase, ZINC ION | 著者 | Martin, P.D, Purcarea, C, Zhang, P, Vaishnav, A, Sadecki, S, Guy-Evans, H.I, Evans, D.R, Edwards, B.F. | 登録日 | 2004-10-15 | 公開日 | 2005-07-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.609 Å) | 主引用文献 | The crystal structure of a novel, latent dihydroorotase from Aquifex aeolicus at 1.7A resolution J.Mol.Biol., 348, 2005
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3P4F
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![BU of 3p4f by Molmil](/molmil-images/mine/3p4f) | Structural and biochemical insights into MLL1 core complex assembly and regulation. | 分子名称: | Histone-lysine N-methyltransferase MLL, Retinoblastoma-binding protein 5, WD repeat-containing protein 5 | 著者 | Avdic, V, Zhang, P, Lanouette, S, Groulx, A, Tremblay, V, Brunzelle, J.B, Couture, J.-F. | 登録日 | 2010-10-06 | 公開日 | 2010-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and biochemical insights into MLL1 core complex assembly. Structure, 19, 2011
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5XSJ
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![BU of 5xsj by Molmil](/molmil-images/mine/5xsj) | XylFII-LytSN complex | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS, ... | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | 登録日 | 2017-06-14 | 公開日 | 2017-08-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XSD
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![BU of 5xsd by Molmil](/molmil-images/mine/5xsd) | XylFII-LytSN complex mutant - D103A | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, Signal transduction histidine kinase, LytS | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | 登録日 | 2017-06-13 | 公開日 | 2017-08-02 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5XSS
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![BU of 5xss by Molmil](/molmil-images/mine/5xss) | XylFII molecule | 分子名称: | Periplasmic binding protein/LacI transcriptional regulator, beta-D-xylopyranose | 著者 | Li, J.X, Wang, C.Y, Zhang, P. | 登録日 | 2017-06-15 | 公開日 | 2017-08-02 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.093 Å) | 主引用文献 | Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4HZL
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![BU of 4hzl by Molmil](/molmil-images/mine/4hzl) | |
6K9K
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![BU of 6k9k by Molmil](/molmil-images/mine/6k9k) | Monomeric human ATM (Ataxia telangiectasia mutated) kinase | 分子名称: | Serine-protein kinase ATM | 著者 | Xiao, J, Liu, M, Qi, Y, Yuriy, C, Zhang, P, Xu, Y. | 登録日 | 2019-06-16 | 公開日 | 2019-12-25 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (7.82 Å) | 主引用文献 | Structural insights into the activation of ATM kinase. Cell Res., 29, 2019
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7E1H
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![BU of 7e1h by Molmil](/molmil-images/mine/7e1h) | crystal structure of RD-BEF | 分子名称: | BERYLLIUM TRIFLUORIDE ION, DNA-binding response regulator, MAGNESIUM ION | 著者 | Hong, S, Zhang, X, Zhang, P. | 登録日 | 2021-02-01 | 公開日 | 2022-02-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | 主引用文献 | Structural basis of phosphorylation-induced activation of the response regulator VbrR. Acta Biochim.Biophys.Sin., 2023
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7E1B
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![BU of 7e1b by Molmil](/molmil-images/mine/7e1b) | Crystal structure of VbrR-DNA complex | 分子名称: | DNA (26-MER), DNA-binding response regulator | 著者 | Hong, S, Zhang, X, Zhang, P. | 登録日 | 2021-02-01 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (4.587 Å) | 主引用文献 | Structural basis of phosphorylation-induced activation of the response regulator VbrR. Acta Biochim.Biophys.Sin., 2023
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8A1S
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![BU of 8a1s by Molmil](/molmil-images/mine/8a1s) | Structure of murine perforin-2 (Mpeg1) pore in twisted form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Macrophage-expressed gene 1 protein | 著者 | Yu, X, Ni, T, Zhang, P, Gilbert, R. | 登録日 | 2022-06-02 | 公開日 | 2022-07-20 | 最終更新日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation. Embo J., 41, 2022
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8A1D
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![BU of 8a1d by Molmil](/molmil-images/mine/8a1d) | Structure of murine perforin-2 (Mpeg1) pore in ring form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, Macrophage-expressed gene 1 protein | 著者 | Yu, X, Ni, T, Zhang, P, Gilbert, R. | 登録日 | 2022-06-01 | 公開日 | 2022-07-20 | 最終更新日 | 2022-12-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Cryo-EM structures of perforin-2 in isolation and assembled on a membrane suggest a mechanism for pore formation. Embo J., 41, 2022
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7EGK
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![BU of 7egk by Molmil](/molmil-images/mine/7egk) | Bicarbonate transporter complex SbtA-SbtB bound to AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, Membrane-associated protein SbtB, SODIUM ION, ... | 著者 | Fang, S, Huang, X, Zhang, X, Zhang, P. | 登録日 | 2021-03-24 | 公開日 | 2021-05-26 | 最終更新日 | 2021-06-16 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA. Proc.Natl.Acad.Sci.USA, 118, 2021
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7EGL
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![BU of 7egl by Molmil](/molmil-images/mine/7egl) | Bicarbonate transporter complex SbtA-SbtB bound to HCO3- | 分子名称: | BICARBONATE ION, Membrane-associated protein SbtB, SODIUM ION, ... | 著者 | Fang, S, Huang, X, Zhang, X, Zhang, P. | 登録日 | 2021-03-24 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular mechanism underlying transport and allosteric inhibition of bicarbonate transporter SbtA. Proc.Natl.Acad.Sci.USA, 118, 2021
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3S32
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![BU of 3s32 by Molmil](/molmil-images/mine/3s32) | Crystal structure of Ash2L N-terminal domain | 分子名称: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | 著者 | Sarvan, S, Avdic, V, Tremblay, V, Chaturvedi, C.-P, Zhang, P, Lanouette, S, Blais, A, Brunzelle, J.S, Brand, M, Couture, J.-F. | 登録日 | 2011-05-17 | 公開日 | 2011-06-08 | 最終更新日 | 2012-01-11 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain. Nat.Struct.Mol.Biol., 18, 2011
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3PSL
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![BU of 3psl by Molmil](/molmil-images/mine/3psl) | Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic | 分子名称: | N-alpha acetylated form of histone H3, WD repeat-containing protein 5 | 著者 | Avdic, V, Zhang, P, Lanouette, S, Voronova, A, Skerjanc, I, Couture, J.-F. | 登録日 | 2010-12-01 | 公開日 | 2010-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic. Faseb J., 25, 2011
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7CSD
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![BU of 7csd by Molmil](/molmil-images/mine/7csd) | AtPrR1 with NADP+ and (+)lariciresinol | 分子名称: | 4-[[(3R,4R,5S)-4-(hydroxymethyl)-5-(3-methoxy-4-oxidanyl-phenyl)oxolan-3-yl]methyl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1 | 著者 | Shao, K, Zhang, P. | 登録日 | 2020-08-14 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.79709971 Å) | 主引用文献 | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nat Commun, 12, 2021
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7CS2
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![BU of 7cs2 by Molmil](/molmil-images/mine/7cs2) | Apo structure of dimeric IiPLR1 | 分子名称: | Pinoresinol-lariciresinol reductase | 著者 | Shao, K, Zhang, P. | 登録日 | 2020-08-14 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.68800473 Å) | 主引用文献 | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nat Commun, 12, 2021
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7CS6
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![BU of 7cs6 by Molmil](/molmil-images/mine/7cs6) | IiPLR1 with NADP+ and (-)lariciresinol | 分子名称: | 4-[[(3S,4S,5R)-4-(hydroxymethyl)-5-(3-methoxy-4-oxidanyl-phenyl)oxolan-3-yl]methyl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol-lariciresinol reductase | 著者 | Shao, K, Zhang, P. | 登録日 | 2020-08-14 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.20139647 Å) | 主引用文献 | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nat Commun, 12, 2021
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7CS8
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![BU of 7cs8 by Molmil](/molmil-images/mine/7cs8) | IiPLR1 with NADP+ and (-)secoisolariciresinol | 分子名称: | (2R,3R)-2,3-bis[(3-methoxy-4-oxidanyl-phenyl)methyl]butane-1,4-diol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol-lariciresinol reductase | 著者 | Shao, K, Zhang, P. | 登録日 | 2020-08-14 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.60003257 Å) | 主引用文献 | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nat Commun, 12, 2021
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7CSC
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![BU of 7csc by Molmil](/molmil-images/mine/7csc) | AtPrR1 with NADP+ and (-)pinoresinol | 分子名称: | 4-[(3R,3aS,6R,6aS)-6-(3-methoxy-4-oxidanyl-phenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxy-phenol, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pinoresinol reductase 1 | 著者 | Shao, K, Zhang, P. | 登録日 | 2020-08-14 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5151186 Å) | 主引用文献 | Structure-based engineering of substrate specificity for pinoresinol-lariciresinol reductases. Nat Commun, 12, 2021
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