4HZL

Neutralizing antibody mAb#8 in complex with the Epitope II of HCV E2 envelope protein

Summary for 4HZL

• Entry DOI: 10.2210/pdb4hzl/pdb
• Descriptor: Fab heavy chain, Fab light chain, E2 envelop protein, ... (4 entities in total)
• Functional Keywords: ig domain, neutralizing antibody, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 6
• Total formula weight: 99218.81

Authors

Deng, L.,Zhang, P. (deposition date: 2012-11-15, release date: 2013-05-01, Last modification date: 2023-09-20)

• Primary citation: Deng, L.,Zhong, L.,Struble, E.,Duan, H.,Ma, L.,Harman, C.,Yan, H.,Virata-Theimer, M.L.,Zhao, Z.,Feinstone, S.,Alter, H.,Zhang, P.; Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus.; Proc.Natl.Acad.Sci.USA, 110:7418-7422, 2013; PubMed: 23589879; DOI: 10.1073/pnas.1305306110

Experimental method

X-RAY DIFFRACTION (2.85 Å)