6BYR

Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PKAc alpha

Summary for 6BYR

Entry DOI	10.2210/pdb6byr/pdb
Descriptor	DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha chimera, cAMP-dependent protein kinase type I-alpha regulatory subunit, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywords	protein complex, pka holoenzyme, fibrolamellar hepatocellular carcinoma, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	181928.32
Authors	Cao, B.,Lu, T.W.,Martinez Fiesco, J.A.,Tomasini, M.,Fan, L.,Simon, S.M.,Taylor, S.S.,Zhang, P. (deposition date: 2017-12-21, release date: 2019-04-03, Last modification date: 2023-10-04)
Primary citation	Cao, B.,Lu, T.W.,Martinez Fiesco, J.A.,Tomasini, M.,Fan, L.,Simon, S.M.,Taylor, S.S.,Zhang, P. Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha. Structure, 27:816-, 2019 Cited by PubMed: 30905674 DOI: 10.1016/j.str.2019.03.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.661 Å)

Structure validation