6BYR

Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PKAc alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha chimera	polymer	405	47591.9	2	UniProt (P25685) UniProt (P17612) Pfam (PF00226) Pfam (PF00069)	Homo sapiens (Human)	DnaJ protein homolog 1,Heat shock 40 kDa protein 1,Heat shock protein 40,Human DnaJ protein 1,hDj-1,PKA C-alpha
2	B, D (B, D)	cAMP-dependent protein kinase type I-alpha regulatory subunit	polymer	379	42816.4	2	UniProt (P00514) Pfam (PF02197) Pfam (PF00027)	Bos taurus (Bovine)
3	E, H (A, C)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
4	F, G, I, J (A, C)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)

Sequence modifications

A, C: 1 - 69 (UniProt: P25685)
A, C: 70 - 405 (UniProt: P17612)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	180816.7
Non-Polymers*	Number of molecules	6
	Total formula weight	1111.6
All*	Total formula weight	181928.3

*Water molecules are not included.