3PSL
Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic
Summary for 3PSL
Entry DOI | 10.2210/pdb3psl/pdb |
Descriptor | WD repeat-containing protein 5, N-alpha acetylated form of histone H3 (3 entities in total) |
Functional Keywords | chromatin, histone, beta-propeller, scaffolding, rbbp5, mll1, nucleus, transcription - transcription inhibitor complex, transcription-transcription inhibitor complex, transcription/transcription inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P61964 |
Total number of polymer chains | 4 |
Total formula weight | 70850.37 |
Authors | Avdic, V.,Zhang, P.,Lanouette, S.,Voronova, A.,Skerjanc, I.,Couture, J.-F. (deposition date: 2010-12-01, release date: 2010-12-22, Last modification date: 2023-09-06) |
Primary citation | Avdic, V.,Zhang, P.,Lanouette, S.,Voronova, A.,Skerjanc, I.,Couture, J.F. Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic. Faseb J., 25:960-967, 2011 Cited by PubMed: 21135039DOI: 10.1096/fj.10-171959 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report