3PSL
Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3 based peptide mimetic
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | WD repeat-containing protein 5 | polymer | 318 | 34794.4 | 2 | UniProt (P61964) Pfam (PF00400) | Homo sapiens (human) | BMP2-induced 3-kb gene protein |
| 2 | C, D (C, D) | N-alpha acetylated form of histone H3 | polymer | 6 | 630.7 | 2 | |||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence modifications
A, B: 21 - 334 (UniProt: P61964)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Ala 18 | - | expression tag |
| Met 19 | - | expression tag |
| Gly 20 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 70850.4 | |
| All* | Total formula weight | 70850.4 |
