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3L2J
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BU of 3l2j by Molmil
Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R)
分子名称: Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pioszak, A.A, Xu, H.E.
登録日2009-12-15
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation.
J.Biol.Chem., 285, 2010
3L3Z
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BU of 3l3z by Molmil
Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid receptor coactivator 3
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 3
著者Zhou, X.E, Suino-Powell, K.M, Li, J, He, A, MacKeigan, J.P, Melcher, K, Yong, E.-L, Xu, H.E.
登録日2009-12-18
公開日2010-01-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
3L3X
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BU of 3l3x by Molmil
Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid receptor coactivator 3
分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 3
著者Zhou, X.E, Suino-Powell, K.M, Li, J, He, A, MacKeigan, J.P, Melcher, K, Yong, E.-L, Xu, H.E.
登録日2009-12-18
公開日2010-01-12
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
J.Biol.Chem., 285, 2010
3N96
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Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1
分子名称: Maltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N93
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BU of 3n93 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3
分子名称: GLYCEROL, Maltose binding protein-CRFR2 alpha, Urocortin-3, ...
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N95
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BU of 3n95 by Molmil
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2
分子名称: Maltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N94
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Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain
分子名称: Fusion protein of Maltose-binding periplasmic protein and pituitary adenylate cyclase 1 Receptor-short, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Kumar, S, Pioszak, A.A, Swaminathan, K, Xu, H.E.
登録日2010-05-28
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors.
Plos One, 6, 2011
4IAR
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BU of 4iar by Molmil
Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)
分子名称: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Ergotamine
著者Wang, C, Jiang, Y, Ma, J, Wu, H, Wacker, D, Katritch, V, Han, G.W, Liu, W, Huang, X, Vardy, E, McCorvy, J.D, Gao, X, Zhou, E.X, Melcher, K, Zhang, C, Bai, F, Yang, H, Yang, L, Jiang, H, Roth, B.L, Cherezov, V, Stevens, R.C, Xu, H.E, GPCR Network (GPCR)
登録日2012-12-07
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4P6X
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BU of 4p6x by Molmil
Crystal Structure of cortisol-bound glucocorticoid receptor ligand binding domain
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, Glucocorticoid receptor, Nuclear receptor coactivator 2
著者He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E.
登録日2014-03-25
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures and mechanism for the design of highly potent glucocorticoids.
Cell Res., 24, 2014
4P6W
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Crystal Structure of mometasone furoate-bound glucocorticoid receptor ligand binding domain
分子名称: Glucocorticoid receptor, MOMETASONE FUROATE, Nuclear receptor coactivator 2
著者He, Y, Zhou, X.E, Tolbert, W.D, Powell, K, Melcher, K, Xu, H.E.
登録日2014-03-25
公開日2014-04-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Structures and mechanism for the design of highly potent glucocorticoids.
Cell Res., 24, 2014
4NUF
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BU of 4nuf by Molmil
Crystal Structure of SHP/EID1
分子名称: EID1 peptide, Maltose ABC transporter periplasmic protein, Nuclear receptor subfamily 0 group B member 2 chimeric construct, ...
著者Zhi, X, Zhou, X.E, He, Y, Zechner, C, Suino-Powell, K.M, Kliewer, S.A, Melcher, K, Mangelsdorf, D.J, Xu, H.E.
登録日2013-12-03
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into gene repression by the orphan nuclear receptor SHP.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PW2
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BU of 4pw2 by Molmil
Crystal structure of D-glucuronyl C5 epimerase
分子名称: CITRIC ACID, D-glucuronyl C5 epimerase B
著者Ke, J, Qin, Y, Gu, X, Brunzelle, J.S, Xu, H.E, Ding, K.
登録日2014-03-18
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and Functional Study of d-Glucuronyl C5-epimerase.
J.Biol.Chem., 290, 2015
4LEU
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BU of 4leu by Molmil
Crystal Structure of THA8-like protein from Arabidopsis thaliana
分子名称: Pentatricopeptide repeat-containing protein At3g46870
著者Ke, J, Chen, R.Z, Ban, T, Brunzelle, J.S, Gu, X, Kang, Y, Melcher, K, Zhu, J.K, Xu, H.E.
登録日2013-06-26
公開日2013-09-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of a PLS-class Pentatricopeptide Repeat Protein Provides Insights into Mechanism of RNA Recognition.
J.Biol.Chem., 288, 2013
4IAQ
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BU of 4iaq by Molmil
Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with dihydroergotamine (PSI Community Target)
分子名称: Chimera protein of human 5-hydroxytryptamine receptor 1B and E. Coli soluble cytochrome b562, Dihydroergotamine
著者Wang, C, Jiang, Y, Ma, J, Wu, H, Wacker, D, Katritch, V, Han, G.W, Liu, W, Huang, X, Vardy, E, McCorvy, J.D, Gao, X, Zhou, E.X, Melcher, K, Zhang, C, Bai, F, Yang, H, Yang, L, Jiang, H, Roth, B.L, Cherezov, V, Stevens, R.C, Xu, H.E, GPCR Network (GPCR)
登録日2012-12-07
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for molecular recognition at serotonin receptors.
Science, 340, 2013
4IB4
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BU of 4ib4 by Molmil
Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHOLESTEROL, ...
著者Wacker, D, Wang, C, Katritch, V, Han, G.W, Huang, X, Vardy, E, McCorvy, J.D, Jiang, Y, Chu, M, Siu, F.Y, Liu, W, Xu, H.E, Cherezov, V, Roth, B.L, Stevens, R.C, GPCR Network (GPCR)
登録日2012-12-07
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural features for functional selectivity at serotonin receptors.
Science, 340, 2013
4N2S
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BU of 4n2s by Molmil
Crystal Structure of THA8 in complex with Zm1a-6 RNA
分子名称: THA8 RNA binding protein, Zm1a-6 RNA
著者Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E.
登録日2013-10-06
公開日2013-10-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4N2Q
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Crystal structure of THA8 in complex with Zm4 RNA
分子名称: RNA (5'-R(*AP*AP*GP*AP*AP*GP*AP*AP*AP*UP*UP*GP*G)-3'), THA8 RNA binding protein
著者Ke, J, Chen, R.Z, Ban, T, Zhou, X.E, Gu, X, Brunzelle, J.S, Zhu, J.K, Melcher, K, Xu, H.E.
登録日2013-10-06
公開日2013-10-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4PXQ
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BU of 4pxq by Molmil
Crystal structure of D-glucuronyl C5-epimerase in complex with heparin hexasaccharide
分子名称: 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, D-glucuronyl C5 epimerase B
著者Ke, J, Qin, Y, Gu, X, Tan, J, Brunzelle, J.S, Xu, H.E, Ding, K.
登録日2014-03-24
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Study of d-Glucuronyl C5-epimerase.
J.Biol.Chem., 290, 2015
4ME2
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BU of 4me2 by Molmil
Crystal Structure of THA8 protein from Brachypodium distachyon
分子名称: Uncharacterized protein
著者Ke, J, Chen, R.Z, Ban, T, Brunzelle, J.S, Gu, X, Melcher, K, Xu, H.E.
登録日2013-08-24
公開日2013-10-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for RNA recognition by a dimeric PPR-protein complex.
Nat.Struct.Mol.Biol., 20, 2013
4IUA
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BU of 4iua by Molmil
Crystal Structure of the NK2 Fragment (31-290) of the mouse Hepatocyte Growth Factor/Scatter Factor
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hepatocyte growth factor, SULFATE ION
著者Tolbert, W.D, Zhou, E, Kovach, A, Melcher, K, Xu, H.E.
登録日2013-01-20
公開日2013-02-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Crystal Structure of the NK2 Fragment of the mouse Hepatocyte Growth Factor/Scatter Factor
To be Published
4LRH
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BU of 4lrh by Molmil
Crystal structure of human folate receptor alpha in complex with folic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, Folate receptor alpha
著者Ke, J, Chen, C, Zhou, X.E, Yi, W, Brunzelle, J.S, Li, J, Young, E.-L, Xu, H.E, Melcher, K.
登録日2013-07-19
公開日2013-07-31
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for molecular recognition of folic acid by folate receptors.
Nature, 500, 2013
5VR7
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BU of 5vr7 by Molmil
ABA-mimicking ligand AMF1alpha in complex with ABA receptor PYL2 and PP2C HAB1
分子名称: 1-(2-fluoro-4-methylphenyl)-N-(2-oxo-1-propyl-1,2,3,4-tetrahydroquinolin-6-yl)methanesulfonamide, Abscisic acid receptor PYL2, MAGNESIUM ION, ...
著者Cao, M.-J, Zhang, Y.-L, Liu, X, Huang, H, Zhou, X.E, Wang, W.-L, Zeng, A, Zhao, C.-Z, Si, T, Du, J.-M, Wu, W.-W, Wang, F.-X, Xu, H.E, Zhu, J.-K.
登録日2017-05-10
公開日2017-11-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.612 Å)
主引用文献Combining chemical and genetic approaches to increase drought resistance in plants.
Nat Commun, 8, 2017
8IBV
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BU of 8ibv by Molmil
Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ...
著者Jiang, Y, Xu, H.E, You, C, Xu, Y.
登録日2023-02-10
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
8IBU
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Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex
分子名称: ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者You, C, Jiang, Y, Xu, H.E, Xu, Y.
登録日2023-02-10
公開日2023-04-12
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
5W0P
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BU of 5w0p by Molmil
Crystal structure of rhodopsin bound to visual arrestin determined by X-ray free electron laser
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endolysin,Rhodopsin,S-arrestin
著者Zhou, X.E, He, Y, de Waal, P.W, Gao, X, Kang, Y, Van Eps, N, Yin, Y, Pal, K, Goswami, D, White, T.A, Barty, A, Latorraca, N.R, Chapman, H.N, Hubbell, W.L, Dror, R.O, Stevens, R.C, Cherezov, V, Gurevich, V.V, Griffin, P.R, Ernst, O.P, Melcher, K, Xu, H.E.
登録日2017-05-31
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.013 Å)
主引用文献Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors.
Cell, 170, 2017

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