3L3X
Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid receptor coactivator 3
Summary for 3L3X
Entry DOI | 10.2210/pdb3l3x/pdb |
Related | 3L3Z |
Descriptor | Androgen receptor, Nuclear receptor coactivator 3, 5-ALPHA-DIHYDROTESTOSTERONE, ... (4 entities in total) |
Functional Keywords | androgen receptor, ligand binding domain, steroid receptor coactivator 3, 5-alpha-dihydrotestosterone (dht), prostate cancer, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : P10275 Cytoplasm: Q9Y6Q9 |
Total number of polymer chains | 2 |
Total formula weight | 30797.27 |
Authors | Zhou, X.E.,Suino-Powell, K.M.,Li, J.,He, A.,MacKeigan, J.P.,Melcher, K.,Yong, E.-L.,Xu, H.E. (deposition date: 2009-12-18, release date: 2010-01-12, Last modification date: 2017-11-01) |
Primary citation | Zhou, X.E.,Suino-Powell, K.M.,Li, J.,He, Y.,Mackeigan, J.P.,Melcher, K.,Yong, E.L.,Xu, H.E. Identification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor. J.Biol.Chem., 285:9161-9171, 2010 Cited by PubMed: 20086010DOI: 10.1074/jbc.M109.085779 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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