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3N96

Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1

Summary for 3N96
Entry DOI10.2210/pdb3n96/pdb
Related3N93 3N95
Related PRD IDPRD_900001
DescriptorMaltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywordsclass b-gpcr, extracellular domain, crfr2 alpha extracellular domain, neuropeptide, selectivity, membrane protein, hormone
Biological sourceHomo sapiens (human)
More
Total number of polymer chains8
Total formula weight221752.71
Authors
Pal, K.,Swaminathan, K.,Pioszak, A.A.,Xu, H.E. (deposition date: 2010-05-28, release date: 2010-10-20, Last modification date: 2023-09-06)
Primary citationPal, K.,Swaminathan, K.,Pioszak, A.A.,Xu, H.E.
Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published,
Experimental method
X-RAY DIFFRACTION (2.75 Å)
Structure validation

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