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3N95

Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2

Summary for 3N95
Entry DOI10.2210/pdb3n95/pdb
Related3N93 3N96
Related PRD IDPRD_900001
DescriptorMaltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (4 entities in total)
Functional Keywordsclass b-gpcr, extracellular domain, crfr2 alpha extracellular domain, neuropeptide, selectivity, membrane protein, hormone
Biological sourceHomo sapiens
More
Total number of polymer chains6
Total formula weight217440.16
Authors
Pal, K.,Swaminathan, K.,Pioszak, A.A.,Xu, H.E. (deposition date: 2010-05-28, release date: 2010-10-20, Last modification date: 2023-09-06)
Primary citationPal, K.,Swaminathan, K.,Pioszak, A.A.,Xu, H.E.
Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published,
Experimental method
X-RAY DIFFRACTION (2.72 Å)
Structure validation

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