3N95
Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Maltose binding protein-CRFR2 alpha extracellular domain | polymer | 482 | 53146.7 | 4 | Pfam (PF01547) Pfam (PF02793) UniProt (by SIFTS) (P0AEX9) UniProt (by SIFTS) (Q13324) In PDB | Homo sapiens | |
| 2 | E, F | Urocortin-2 | polymer | 17 | 1742.0 | 2 | UniProt (Q96RP3) Pfam (PF00473) In PDB | Urocortin II, Ucn II, Stresscopin-related peptide, Urocortin-related peptide | |
| 3 | G, H, I, J | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | branched | 342.3 | 4 | In PDB BIRD (PRD_900001) GlyTouCan (G07411ON) | alpha-maltose | ||
| 4 | water | water | 18.0 | 272 | Chemie (HOH) |
Sequence modifications
E, F: 26 - 41 (UniProt: Q96RP3)
| PDB | External Database | Details |
|---|---|---|
| Nh2 42 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 216071.0 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1369.2 | |
| All* | Total formula weight | 217440.2 |
