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7NIV
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BU of 7niv by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation)
分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment light chain, CHOLESTEROL, ...
著者Nosol, K, Locher, K.P.
登録日2021-02-14
公開日2021-08-25
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7NIW
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BU of 7niw by Molmil
Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab (posaconazole-bound, inward-open conformation)
分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, ...
著者Nosol, K, Locher, K.P.
登録日2021-02-14
公開日2021-08-25
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of ABCB4 provide insight into phosphatidylcholine translocation.
Proc.Natl.Acad.Sci.USA, 118, 2021
5VKD
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BU of 5vkd by Molmil
Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment
分子名称: Fab Heavy Chain, Fab light chain, Nucleoprotein
著者Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S.
登録日2017-04-21
公開日2018-04-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.749 Å)
主引用文献The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Acta Crystallogr D Struct Biol, 74, 2018
7PGB
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BU of 7pgb by Molmil
NaV_Ae1/Sp1CTD_pore-SAT09 complex
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4-NITROBENZOIC ACID, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PG8
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BU of 7pg8 by Molmil
NaV_Ae1/Sp1CTD_pore-ANT05 complex
分子名称: ANT05 H12 fab fragment, heavy chain, light chain, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGF
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BU of 7pgf by Molmil
Calcium-selective Sp1 channel pore domain only
分子名称: Ion transporter
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-08
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGI
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BU of 7pgi by Molmil
NaVAb1p (bicelles)
分子名称: ACETATE ION, Ion transport protein, MAGNESIUM ION, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-14
公開日2022-06-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.638 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGH
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BU of 7pgh by Molmil
NaVAe1/Sp1CTDp (DDM)
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, DODECAETHYLENE GLYCOL, DODECANE, ...
著者Lolicato, M, Arrigoni, C.
登録日2021-08-14
公開日2022-06-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (4.194 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
7PGG
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BU of 7pgg by Molmil
NaVAb1p detergent (DM)
分子名称: 2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}ethyl heptadecanoate, Ion transport protein
著者Lolicato, M, Arrigoni, C.
登録日2021-08-13
公開日2022-06-15
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Quaternary structure independent folding of voltage-gated ion channel pore domain subunits.
Nat.Struct.Mol.Biol., 29, 2022
8VC7
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BU of 8vc7 by Molmil
Crystal Structure of Human BTN2A1 ectodomain in complex with Antagonist 2A1.9 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Butyrophilin subfamily 2 member A1, Human IgG1 Fragment Antibody Heavy Chain, ...
著者Ramesh, A, Roy, S, Adams, E.
登録日2023-12-13
公開日2024-12-18
最終更新日2025-04-23
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Mapping the extracellular molecular architecture of the pAg-signaling complex with alpha-Butyrophilin antibodies.
Sci Rep, 15, 2025
8VJ9
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BU of 8vj9 by Molmil
CryoEM structure of human ACKR3 phosphorylated by GRK5 in complex with Arrestin3 variant with the C edge loop from Arrestin2 inserted
分子名称: Atypical chemokine receptor 3, Beta-arrestin-2, Fab7 heavy chain, ...
著者Chen, Q, Tesmer, J.J.G.
登録日2024-01-06
公開日2025-01-22
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor.
Nature, 643, 2025
6VI2
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BU of 6vi2 by Molmil
Structure of the unaligned Fab4
分子名称: FAB4 heavy chain, FAB4 light chain
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
8VZN
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BU of 8vzn by Molmil
Cryo-EM structure of FLVCR2 in the inward-facing state with choline bound
分子名称: CHOLINE ION, Fab FLV9 heavy chain, Fab FLV9 light chain, ...
著者Cater, R.J, Mancia, F.
登録日2024-02-12
公開日2024-05-01
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.77 Å)
主引用文献Structural and molecular basis of choline uptake into the brain by FLVCR2.
Nature, 629, 2024
8VZO
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BU of 8vzo by Molmil
Cryo-EM structure of FLVCR2 in the outward-facing state with choline bound
分子名称: CHOLINE ION, Fab FLV23 heavy chain, Fab FLV23 light chain, ...
著者Cater, R.J, Mancia, F.
登録日2024-02-12
公開日2024-05-01
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Structural and molecular basis of choline uptake into the brain by FLVCR2.
Nature, 629, 2024
8VTI
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BU of 8vti by Molmil
Latrophilin-3 (ADGRL3) HormR and GAIN domains in the context of the holoreceptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 4 of Adhesion G protein-coupled receptor L3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kordon, S.P, Bandekar, S.J, Arac, D.
登録日2024-01-26
公開日2024-12-11
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Conformational coupling between extracellular and transmembrane domains modulates holo-adhesion GPCR function.
Nat Commun, 15, 2024
6VI1
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BU of 6vi1 by Molmil
Structure of Fab4 bound to P22 TerL(1-33)
分子名称: Synthetic Fab4 heavy chain, Synthetic Fab4 light chain, Terminase, ...
著者Cingolani, G, Lokareddy, R, Ko, Y.
登録日2020-01-11
公開日2020-09-02
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of an alpha-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Acta Crystallogr D Struct Biol, 76, 2020
5CJO
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BU of 5cjo by Molmil
Crystal Structure Analysis of Elbow-Engineered-Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FAB Heavy chain with engineered elbow, FAB light chain, ...
著者liang, w.g, bailey, L, tang, w.j.
登録日2015-07-14
公開日2016-07-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.287 Å)
主引用文献Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 2017
7KEO
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BU of 7keo by Molmil
Crystal structure of K29-linked di-ubiquitin in complex with synthetic antigen binding fragment
分子名称: PHOSPHATE ION, Synthetic antigen binding fragment, heavy chain, ...
著者Yu, Y, Zheng, Q, Erramilli, S, Pan, M, Kossiakoff, A, Liu, L, Zhao, M.
登録日2020-10-11
公開日2021-07-28
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Nat.Chem.Biol., 17, 2021
7MDJ
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BU of 7mdj by Molmil
The structure of KcsA in complex with a synthetic Fab
分子名称: Fab heavy chain, Fab light chain, POTASSIUM ION, ...
著者Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B.
登録日2021-04-05
公開日2022-02-16
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
J.Gen.Physiol., 154, 2022
9PTI
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BU of 9pti by Molmil
BASIC PANCREATIC TRYPSIN INHIBITOR (MET 52 OXIDIZED)
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
著者Eigenbrot, C, Randal, M, Kossiakoff, A.A.
登録日1991-04-08
公開日1992-04-15
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献

7RU6
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BU of 7ru6 by Molmil
Cryo-EM structure of the HIV-1 restriction factor human SERINC3
分子名称: Serine incorporator 3, SiA
著者Purdy, M.D, Leonhardt, S.A, Yeager, M.
登録日2021-08-16
公開日2022-08-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.
Nat Commun, 14, 2023
7RUG
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BU of 7rug by Molmil
Human SERINC3-DeltaICL4
分子名称: Serine incorporator 3, SiA
著者Purdy, M.D, Leonhardt, S.A, Yeager, M.
登録日2021-08-17
公開日2022-08-24
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.
Nat Commun, 14, 2023
7TDN
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BU of 7tdn by Molmil
CryoEM Structure of sFab COP-3 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
分子名称: COP-3 Fab Heavy chain, COP-3 Fab Light chain, Claudin-4, ...
著者Vecchio, A.J.
登録日2022-01-01
公開日2022-02-09
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
7TDM
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BU of 7tdm by Molmil
CryoEM Structure of sFab COP-2 Complex with human claudin-4 and Clostridium perfringens enterotoxin C-terminal domain
分子名称: COP-2 Fab Heavy chain, COP-2 Fab Light chain, Claudin-4, ...
著者Vecchio, A.J.
登録日2022-01-01
公開日2022-02-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Development, structure, and mechanism of synthetic antibodies that target claudin and Clostridium perfringens enterotoxin complexes.
J.Biol.Chem., 298, 2022
7T9X
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BU of 7t9x by Molmil
Saccharomyces cerevisiae Pex12 RING domain
分子名称: Peroxisome assembly protein 12, ZINC ION
著者Feng, P, Rapoport, T.
登録日2021-12-20
公開日2022-06-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
Nature, 607, 2022

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件を2025-07-09に公開中

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