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7LIR
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BU of 7lir by Molmil
Structure of the invertebrate ALK GRD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor homolog scd-2, ...
著者Stayrook, S, Li, T, Klein, D.E.
登録日2021-01-27
公開日2021-11-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
7LS0
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BU of 7ls0 by Molmil
Structure of the Human ALK GRD bound to AUG
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALK tyrosine kinase receptor fused with ALK and LTK ligand 2, CITRIC ACID
著者Stayrook, S, Li, T, Klein, D.E.
登録日2021-02-17
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021
4IPX
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BU of 4ipx by Molmil
Analyzing the visible conformational substates of the FK506 binding protein FKBP12
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Peptidyl-prolyl cis-trans isomerase FKBP1A
著者Chen, H, Mustafi, S.M, Li, H.M, LeMaster, D.M, Hernandez, G.
登録日2013-01-10
公開日2013-06-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Analysing the visible conformational substates of the FK506-binding protein FKBP12.
Biochem.J., 453, 2013
5YEI
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BU of 5yei by Molmil
Mechanistic insight into the regulation of Pseudomonas aeruginosa aspartate kinase
分子名称: Aspartokinase, GLYCEROL, LYSINE, ...
著者Li, C, Yang, M, Liu, L, Peng, C, Li, T, He, L, Song, Y, Zhu, Y, Bao, R.
登録日2017-09-17
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Mechanistic insights into the allosteric regulation of Pseudomonas aeruginosa aspartate kinase.
Biochem.J., 475, 2018
5I5F
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BU of 5i5f by Molmil
Salmonella global domain 191
分子名称: Inner membrane protein YejM
著者Dong, C, Dong, H.
登録日2016-02-15
公開日2016-08-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural insights into cardiolipin transfer from the Inner membrane to the outer membrane by PbgA in Gram-negative bacteria.
Sci Rep, 6, 2016
5YLO
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BU of 5ylo by Molmil
Structural of Pseudomonas aeruginosa PA4980
分子名称: GLYCEROL, Probable enoyl-CoA hydratase/isomerase
著者Liu, L, Li, T, Peng, C.T, Li, C.C, Xiao, Q.J, He, L.H, Wang, N.Y, Bao, R.
登録日2017-10-18
公開日2018-08-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structural characterization of a Delta3, Delta2-enoyl-CoA isomerase from Pseudomonas aeruginosa: implications for its involvement in unsaturated fatty acid metabolism.
J.Biomol.Struct.Dyn., 37, 2019
5KWA
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BU of 5kwa by Molmil
complete structure of the Mycobacterium tuberculosis proteasomal ATPase Mpa
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Proteasome-associated ATPase
著者Wang, T, WU, Y.J.
登録日2016-07-17
公開日2017-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mycobacterium tuberculosis proteasomal ATPase Mpa has a beta-grasp domain that hinders docking with the proteasome core protease
Mol. Microbiol., 105, 2017
8XIF
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BU of 8xif by Molmil
The crystal structure of the AEP domain of VACV D5
分子名称: MAGNESIUM ION, PYROPHOSPHATE, Uncoating factor OPG117
著者Gan, J, Zhang, W.
登録日2023-12-19
公開日2024-05-01
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
8XIG
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BU of 8xig by Molmil
The crystal structure of the AEP domain of MPXV E5
分子名称: MAGNESIUM ION, PYROPHOSPHATE, Uncoating factor OPG117
著者Gan, J, Zhang, W.
登録日2023-12-19
公開日2024-05-01
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and functional insights into the helicase protein E5 of Mpox virus.
Cell Discov, 10, 2024
8FK2
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BU of 8fk2 by Molmil
The N-terminal VicR from Streptococcus mutans
分子名称: Putative response regulator CovR VicR-like protein
著者Zhang, H, Wu, H.
登録日2022-12-20
公開日2023-10-25
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator.
Mbio, 14, 2023
7MSQ
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BU of 7msq by Molmil
Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)
分子名称: AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, CHLORIDE ION, ...
著者Langley, D.B, Christ, D.
登録日2021-05-12
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability.
Immunity, 54, 2021
8GQP
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BU of 8gqp by Molmil
Complex of D-protein binder D-19437 and L-target L-Pep-1
分子名称: D-binder, L-pep1
著者Liang, M.F, Li, S.C, Wang, T.Y, Liu, L, Lu, P.L.
登録日2022-08-30
公開日2023-09-13
最終更新日2024-09-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Accurate de novo design of heterochiral protein-protein interactions
Cell Res., 2024
6UL8
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BU of 6ul8 by Molmil
RIP2 kinase catalytic domain complex with (5S,6S,8R)-2-(benzo[d]thiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide
分子名称: (5S,6S,8R)-2-(1,3-benzothiazol-5-yl)-6-hydroxy-4,5,6,7,8,9-hexahydro-5,8-methanopyrazolo[1,5-a][1,3]diazocine-3-carboxamide, CALCIUM ION, Receptor-interacting serine/threonine-protein kinase 2
著者Shewchuk, L.M, Convery, M.A.
登録日2019-10-07
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Discovery of Pyrazolocarboxamides as Potent and Selective Receptor Interacting Protein 2 (RIP2) Kinase Inhibitors.
Acs Med.Chem.Lett., 10, 2019
6IVY
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BU of 6ivy by Molmil
Crystal structure of iron-bound HitA from Pseudomonas aeruginosa
分子名称: FE (III) ION, PHOSPHATE ION, Periplasmic Ferric iron-binding Protein HitA
著者Zhang, Z.R, Li, H.Y.
登録日2018-12-04
公開日2019-12-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9999994 Å)
主引用文献Identification and Characterization of a Metalloprotein Involved in Gallium Internalization in Pseudomonas aeruginosa.
Acs Infect Dis., 5, 2019
6J2S
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BU of 6j2s by Molmil
Structure of HitA bound to gallium from Pseudomonas aeruginosa
分子名称: Ferric iron-binding periplasmic protein, GALLIUM (III) ION, PHOSPHATE ION
著者Guo, Y, Li, H.Y, Sun, H.Z, Xia, W.
登録日2019-01-02
公開日2020-01-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.73005116 Å)
主引用文献Identification and Characterization of a Metalloprotein Involved in Gallium Internalization in Pseudomonas aeruginosa.
Acs Infect Dis., 5, 2019
1G3G
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BU of 1g3g by Molmil
NMR STRUCTURE OF THE FHA1 DOMAIN OF YEAST RAD53
分子名称: PROTEIN KINASE SPK1
著者Yuan, C, Liao, H, Su, M, Yongkiettrakul, S, Byeon, I.-J.L, Tsai, M.-D.
登録日2000-10-24
公開日2001-01-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9
J.Mol.Biol., 304, 2000
6AEX
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BU of 6aex by Molmil
Crystal structure of unoccupied murine uPAR
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Urokinase plasminogen activator surface receptor
著者Min, L, Huang, M.
登録日2018-08-06
公開日2019-07-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.393 Å)
主引用文献Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit.
Febs Lett., 593, 2019
5KUP
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BU of 5kup by Molmil
Bruton's tyrosine kinase (BTK) with pyridazinone compound 9
分子名称: 2-(2-METHOXYETHOXY)ETHANOL, 6-~{tert}-butyl-8-fluoranyl-2-[3-(hydroxymethyl)-4-[1-methyl-6-oxidanylidene-5-(pyrimidin-4-ylamino)pyridin-3-yl]pyridin-2-yl]phthalazin-1-one, GLYCEROL, ...
著者Eigenbrot, C, Yu, C.
登録日2016-07-13
公開日2016-09-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.389 Å)
主引用文献Battling Btk Mutants With Noncovalent Inhibitors That Overcome Cys481 and Thr474 Mutations.
Acs Chem.Biol., 11, 2016
5IMX
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BU of 5imx by Molmil
Anaplastic lymphoma kinase (ALK) catalytic domain complexed with novel inhibitor 3-sulfonylpyrazol-4-amino pyrimidine
分子名称: 5-chloro-N~2~-{5-methyl-4-(1-methylpiperidin-4-yl)-2-[(propan-2-yl)oxy]phenyl}-N~4~-{1-methyl-3-[(propan-2-yl)sulfonyl]-1H-pyrazol-4-yl}pyrimidine-2,4-diamine, ALK tyrosine kinase receptor
著者Wang, C, Zhang, P, Dong, J.
登録日2016-03-07
公開日2016-05-04
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
8I8A
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BU of 8i8a by Molmil
Cryo-EM structure of the major capsid protein VP39 of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
分子名称: Major viral capsid protein
著者Jia, X, Zhang, Q.
登録日2023-02-03
公開日2023-12-13
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
8I8C
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BU of 8i8c by Molmil
Plug structure of the Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
分子名称: Occlusion-derived virus envelope/capsid protein, P40
著者Jia, X, Gao, Y, Zhang, Q.
登録日2023-02-03
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (4.93 Å)
主引用文献Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
8I8B
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BU of 8i8b by Molmil
Outer shell and inner layer structures of Autographa californica multiple nucleopolyhedrovirus (AcMNPV)
分子名称: 38K, AcOrf-109 peptide, Early 49 Daa protein, ...
著者Jia, X, Gao, Y, Zhang, Q.
登録日2023-02-03
公開日2023-12-13
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4.31 Å)
主引用文献Architecture of the baculovirus nucleocapsid revealed by cryo-EM.
Nat Commun, 14, 2023
6IO4
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BU of 6io4 by Molmil
Silver-bound Glyceraldehyde-3-phosphate dehydrogenase A
分子名称: Glyceraldehyde-3-phosphate dehydrogenase A, SILVER ION
著者Wang, H, Sun, H, Wang, M.
登録日2018-10-29
公開日2019-07-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
6IOJ
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BU of 6ioj by Molmil
Glyceraldehyde-3-phosphate dehydrogenase A (apo-form)
分子名称: Glyceraldehyde-3-phosphate dehydrogenase A
著者Wang, H, Sun, H, Wang, M.
登録日2018-10-30
公開日2019-07-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Antimicrobial silver targets glyceraldehyde-3-phosphate dehydrogenase in glycolysis ofE. coli.
Chem Sci, 10, 2019
7MK7
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BU of 7mk7 by Molmil
Augmentor domain of augmentor-beta
分子名称: ALK and LTK ligand 1,Maltodextrin-binding protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Krimmer, S.G, Reshetnyak, A.V, Puleo, D.E, Schlessinger, J.
登録日2021-04-21
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.42815185 Å)
主引用文献Structural basis for ligand reception by anaplastic lymphoma kinase.
Nature, 600, 2021

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