7MSQ

Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)

Summary for 7MSQ

Entry DOI	10.2210/pdb7msq/pdb
Descriptor	Spike protein S1, AB-3467 Fab Heavy Chain, AB-3467 Fab Light Chain, ... (8 entities in total)
Functional Keywords	sars-cov-2 receptor binding domain ab-3467, antiviral protein, viral protein-antiviral protein complex, viral protein/antiviral protein
Biological source	Severe acute respiratory syndrome coronavirus 2 More
Total number of polymer chains	6
Total formula weight	145714.09
Authors	Langley, D.B.,Christ, D. (deposition date: 2021-05-12, release date: 2022-01-19, Last modification date: 2023-10-18)
Primary citation	Burnett, D.L.,Jackson, K.J.L.,Langley, D.B.,Aggrawal, A.,Stella, A.O.,Johansen, M.D.,Balachandran, H.,Lenthall, H.,Rouet, R.,Walker, G.,Saunders, B.M.,Singh, M.,Li, H.,Henry, J.Y.,Jackson, J.,Stewart, A.G.,Witthauer, F.,Spence, M.A.,Hansbro, N.G.,Jackson, C.,Schofield, P.,Milthorpe, C.,Martinello, M.,Schulz, S.R.,Roth, E.,Kelleher, A.,Emery, S.,Britton, W.J.,Rawlinson, W.D.,Karl, R.,Schafer, S.,Winkler, T.H.,Brink, R.,Bull, R.A.,Hansbro, P.M.,Jack, H.M.,Turville, S.,Christ, D.,Goodnow, C.C. Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability. Immunity, 54:2908-2921.e6, 2021 Cited by PubMed: 34788600 DOI: 10.1016/j.immuni.2021.10.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation