7MSQ

Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Spike protein S1	polymer	204	22975.7	2	UniProt (P0DTC2) Pfam (PF09408)	Severe acute respiratory syndrome coronavirus 2	Spike glycoprotein
2	C, E (D, H)	AB-3467 Fab Heavy Chain	polymer	238	25758.7	2		Homo sapiens
3	D, F (E, L)	AB-3467 Fab Light Chain	polymer	214	23359.9	2		Homo sapiens
4	G (C)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		894.8	1	In PDB GlyTouCan (G42466VF)
5	H, I, K, L, N... (A, B, D, E, H)	CHLORIDE ION	non-polymer		35.5	7	Chemie (CL)
6	J, P, R, S, T (B, E, L)	THIOCYANATE ION	non-polymer		58.1	5	Chemie (SCN)
7	M (D)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	U, V, W, X, Y... (A, B, D, E, H...)	water	water		18.0	164	Chemie (HOH)

Sequence modifications

A, B: 333 - 528 (UniProt: P0DTC2)

PDB	External Database	Details
Gly 529	-	expression tag
Ser 530	-	expression tag
His 531	-	expression tag
His 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	144188.6
Branched	Number of molecules	1
	Total formula weight	894.8
Non-Polymers*	Number of molecules	13
	Total formula weight	630.7
All*	Total formula weight	145714.1

*Water molecules are not included.