7MSQ
Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Spike protein S1 | polymer | 204 | 22975.7 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | Spike glycoprotein |
2 | D, H | AB-3467 Fab Heavy Chain | polymer | 238 | 25758.7 | 2 | Homo sapiens | ||
3 | E, L | AB-3467 Fab Light Chain | polymer | 214 | 23359.9 | 2 | Homo sapiens | ||
4 | C | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
5 | A, B, D, E, H | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
6 | B, E, L | THIOCYANATE ION | non-polymer | 58.1 | 5 | Chemie (SCN) | |||
7 | D | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
8 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B: 333 - 528 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Gly 529 | - | expression tag |
Ser 530 | - | expression tag |
His 531 | - | expression tag |
His 532 | - | expression tag |
His 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 144188.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 894.8 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 630.7 | |
All* | Total formula weight | 145714.1 |