8WNH
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7DL9
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7WNH
| Crystal structure of Nurr1 binding to NBRE | 分子名称: | DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), Nuclear receptor subfamily 4 group A member 2, ... | 著者 | Zhao, M, Xu, T, Wang, N, Guo, Y, Liu, J. | 登録日 | 2022-01-18 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXR alpha heterodimer. Proc.Natl.Acad.Sci.USA, 119, 2022
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2H2Z
| Crystal structure of SARS-CoV main protease with authentic N and C-termini | 分子名称: | Replicase polyprotein 1ab | 著者 | Yang, H, Xue, X, Shen, W, Zhao, Q, Rao, Z. | 登録日 | 2006-05-20 | 公開日 | 2007-04-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction J.Mol.Biol., 366, 2007
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3LO2
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2KJD
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5FHZ
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4PHS
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7UDH
| Integrin alaphIIBbeta3 complex with BMS4-3 | 分子名称: | (4-{[(5S)-3-(piperidin-4-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2022-03-19 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.99998844 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UK9
| Integrin alaphIIBbeta3 complex with lamifiban (Mn) | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2022-03-31 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.60001969 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UFH
| Integrin alaphIIBbeta3 complex with fradafiban (Mn/Ca) | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2022-03-22 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.99768162 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UKT
| Integrin alaphIIBbeta3 complex with BMS4.2 | 分子名称: | (1-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperidin-4-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2022-04-01 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.36994433 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UCY
| Integrin alaphIIBbeta3 complex with gantofiban | 分子名称: | (4-{[(5R)-3-(4-carbamimidoylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2022-03-17 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.34996319 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UJK
| Integrin alaphIIBbeta3 complex with lamifiban | 分子名称: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | 登録日 | 2022-03-30 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.43265581 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7U9V
| Integrin alaphIIBbeta3 complex with BMS4-1 | 分子名称: | (4-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 light chain, ... | 著者 | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | 登録日 | 2022-03-11 | 公開日 | 2022-08-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.25492167 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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2KFU
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3LO1
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3LOE
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3LO6
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3LO4
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3LO9
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7DMP
| Mouse radial spoke complex | 分子名称: | Radial spoke head 1 homolog, Radial spoke head protein 4 homolog A, Radial spoke head protein 9 homolog | 著者 | Zheng, W, Cong, Y. | 登録日 | 2020-12-05 | 公開日 | 2021-07-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM Proc.Natl.Acad.Sci.USA, 118, 2021
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4M5C
| Crystal Structure of an Truncated Transition metal Transporter | 分子名称: | COBALT (II) ION, Cobalamin biosynthesis protein CbiM, HEXANE-1,6-DIOL | 著者 | Yu, Y, Zhou, M.Z, Gu, J.K. | 登録日 | 2013-08-08 | 公開日 | 2014-03-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014
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7WK2
| SARS-CoV-2 Omicron S-close | 分子名称: | Spike glycoprotein | 著者 | Li, J.W, Cong, Y. | 登録日 | 2022-01-08 | 公開日 | 2022-01-26 | 最終更新日 | 2022-05-04 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Molecular basis of receptor binding and antibody neutralization of Omicron. Nature, 604, 2022
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7W0G
| Human PPAR delta ligand binding domain in complex with a synthetic agonist H11 | 分子名称: | 2-[2,6-dimethyl-4-[[5-oxidanylidene-4-[4-(trifluoromethyloxy)phenyl]-1,2,4-triazol-1-yl]methyl]phenoxy]-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor delta | 著者 | Dai, L, Sun, H.B, Yuan, H.L, Feng, Z.Q. | 登録日 | 2021-11-18 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.443 Å) | 主引用文献 | Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPAR alpha / delta Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis. J.Med.Chem., 65, 2022
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