7RHP
 
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6IDE
 | | Crystal structure of the Vibrio cholera VqmA-Ligand-DNA complex provides molecular mechanisms for drug design | | 分子名称: | 3,5-dimethylpyrazin-2-ol, DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*AP*AP*TP*CP*CP*CP*CP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*GP*GP*GP*GP*AP*TP*TP*TP*CP*CP*CP*CP*CP*CP*T)-3'), ... | | 著者 | Wu, H, Li, M.J, Guo, H.J, Zhou, H, Li, B, Xu, Q, Xu, C.Y, Yu, F, He, J.H. | | 登録日 | 2018-09-09 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Crystal structure of theVibrio choleraeVqmA-ligand-DNA complex provides insight into ligand-binding mechanisms relevant for drug design.
J. Biol. Chem., 294, 2019
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4QKT
 | | Azurin mutant M121EM44K with copper | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Azurin, ... | | 著者 | Liu, J, Robinson, H, Lu, Y. | | 登録日 | 2014-06-09 | | 公開日 | 2014-08-13 | | 最終更新日 | 2014-10-01 | | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | | 主引用文献 | Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
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4QLW
 | | Azurin mutant M121E with iron | | 分子名称: | Azurin, FE (III) ION, NITRATE ION, ... | | 著者 | Liu, J, Robinson, H, Lu, Y. | | 登録日 | 2014-06-13 | | 公開日 | 2014-08-13 | | 最終更新日 | 2014-10-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin.
J.Am.Chem.Soc., 136, 2014
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6KJU
 | | Huge conformation shift of Vibrio cholerae VqmA dimer in the absence of target DNA provides insight into DNA-binding mechanisms of LuxR-type receptors | | 分子名称: | 3,5-dimethylpyrazin-2-ol, Helix-turn-helix transcriptional regulator | | 著者 | Wu, H, Li, M.J, Guo, H.J, Zhou, H, Wang, W.W, Xu, Q, Xu, C.Y, Yu, F, He, J.H. | | 登録日 | 2019-07-23 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Large conformation shifts of Vibrio cholerae VqmA dimer in the absence of target DNA provide insight into DNA-binding mechanisms of LuxR-type receptors.
Biochem.Biophys.Res.Commun., 520, 2019
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6KZ8
 | | Crystal structure of plant Phospholipase D alpha complex with phosphatidic acid | | 分子名称: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, CALCIUM ION, Phospholipase D alpha 1 | | 著者 | Li, J.X, Yu, F, Zhang, P. | | 登録日 | 2019-09-23 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.291 Å) | | 主引用文献 | Crystal structure of plant PLD alpha 1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D.
Cell Res., 30, 2020
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6KZ9
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5U36
 | | Crystal Structure Of A Mutant M. Jannashii Tyrosyl-tRNA Synthetase | | 分子名称: | Tyrosine--tRNA ligase | | 著者 | Luo, X, Fu, G, Zhu, X, Wilson, I.A, Wang, F. | | 登録日 | 2016-12-01 | | 公開日 | 2017-06-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria.
Nat. Chem. Biol., 13, 2017
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5W0C
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4E1N
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4E1M
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4DWL
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1B0R
 | | CRYSTAL STRUCTURE OF HLA-A*0201 COMPLEXED WITH A PEPTIDE WITH THE CARBOXYL-TERMINAL GROUP SUBSTITUTED BY A METHYL GROUP | | 分子名称: | PROTEIN (HLA-A*0201), PROTEIN (INFLUENZA MATRIX PEPTIDE) | | 著者 | Bouvier, M, Guo, H, Smith, K.J, Wiley, D.C. | | 登録日 | 1998-11-12 | | 公開日 | 1999-11-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of HLA-A*0201 complexed with antigenic peptides with either the amino- or carboxyl-terminal group substituted by a methyl group.
Proteins, 33, 1998
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5H25
 | | EED in complex with PRC2 allosteric inhibitor compound 11 | | 分子名称: | 5-(2-fluorophenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | | 登録日 | 2016-10-14 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy
J. Med. Chem., 60, 2017
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5GM2
 | | Crystal structure of methyltransferase TleD complexed with SAH and teleocidin A1 | | 分子名称: | (2S,5S)-9-[(3R)-3,7-dimethylocta-1,6-dien-3-yl]-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, O-methylransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Yu, F, Li, M.J, Xu, C.Y, Zhou, H, Sun, B, Wang, Z.J, Xu, Q, Xie, M.Y, Zuo, G, Huang, P, Wang, Q.S, He, J.H. | | 登録日 | 2016-07-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD
Biochem.J., 473, 2016
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7WP6
 | | Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ... | | 著者 | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | | 登録日 | 2022-01-23 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (3.81 Å) | | 主引用文献 | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
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7WP8
 | | Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ... | | 著者 | Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N. | | 登録日 | 2022-01-23 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
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5H24
 | | EED in complex with PRC2 allosteric inhibitor compound 8 | | 分子名称: | 5-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-a]pyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | | 登録日 | 2016-10-14 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of First-in-Class, Potent, and Orally Bioavailable Embryonic Ectoderm Development (EED) Inhibitor with Robust Anticancer Efficacy
J. Med. Chem., 60, 2017
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5GM1
 | | Crystal structure of methyltransferase TleD complexed with SAH | | 分子名称: | O-methylransferase, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Yu, F, Li, M.J, Xu, C.Y, Zhou, H, Sun, B, Wang, Z.J, Xu, Q, Xie, M.Y, Zuo, G, Huang, P, Wang, Q.S, He, J.H. | | 登録日 | 2016-07-12 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | Crystal structure and enantioselectivity of terpene cyclization in SAM-dependent methyltransferase TleD
Biochem.J., 473, 2016
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3WLW
 | | Molecular Architecture of the ErbB2 Extracellular Domain Homodimer | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody H Chain, ... | | 著者 | Hu, S, Lou, Z.Y, Guo, Y.J. | | 登録日 | 2013-11-15 | | 公開日 | 2015-05-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.088 Å) | | 主引用文献 | Molecular architecture of the ErbB2 extracellular domain homodimer.
Oncotarget, 6, 2015
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8IX3
 | | Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement) | | 分子名称: | BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11 | | 著者 | Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S. | | 登録日 | 2023-03-31 | | 公開日 | 2023-11-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant.
J.Virol., 97, 2023
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5GT1
 | | crystal structure of cbpa from L. salivarius REN | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Choline binding protein A, ... | | 著者 | Jiang, L, Ren, F. | | 登録日 | 2016-08-18 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The Adhesion of Lactobacillus salivarius REN to a Human Intestinal Epithelial Cell Line Requires S-layer Proteins
Sci Rep, 7, 2017
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5HYX
 | | Plant peptide hormone receptor RGFR1 in complex with RGF1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-SER-ASN-PRO-GLY-HIS-HIS-PRO-HYP-ARG-HIS-ASN, ... | | 著者 | Song, W, Han, Z, Chai, J. | | 登録日 | 2016-02-02 | | 公開日 | 2017-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth
Cell Res., 26, 2016
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7TYG
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7TXH
 | | Human MRas Q71R in complex with human Shoc2 LRR domain M173I and human PP1Ca | | 分子名称: | GLYCEROL, Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, ... | | 著者 | Hauseman, Z.J, Viscomi, J, Dhembi, A, Clark, K, King, D.A, Fodor, M. | | 登録日 | 2022-02-09 | | 公開日 | 2022-06-22 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the MRAS-SHOC2-PP1C phosphatase complex.
Nature, 609, 2022
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