7TYG

Structure of the human leucine rich repeat protein SHOC2, residues 80-582

Summary for 7TYG

• Entry DOI: 10.2210/pdb7tyg/pdb
• Descriptor: Leucine-rich repeat protein SHOC-2, MAGNESIUM ION (3 entities in total)
• Functional Keywords: ras, pp1, shoc2, lrr, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 113499.47

Authors

Dhembi, A.,Clark, K.,King, D.A. (deposition date: 2022-02-13, release date: 2022-06-22, Last modification date: 2023-10-18)

• Primary citation: Hauseman, Z.J.,Fodor, M.,Dhembi, A.,Viscomi, J.,Egli, D.,Bleu, M.,Katz, S.,Park, E.,Jang, D.M.,Porter, K.A.,Meili, F.,Guo, H.,Kerr, G.,Molle, S.,Velez-Vega, C.,Beyer, K.S.,Galli, G.G.,Maira, S.M.,Stams, T.,Clark, K.,Eck, M.J.,Tordella, L.,Thoma, C.R.,King, D.A.; Structure of the MRAS-SHOC2-PP1C phosphatase complex.; Nature, 609:416-423, 2022; PubMed: 35830882; DOI: 10.1038/s41586-022-05086-1

Experimental method

X-RAY DIFFRACTION (1.9 Å)