7TXH

Human MRas Q71R in complex with human Shoc2 LRR domain M173I and human PP1Ca

Summary for 7TXH

• Entry DOI: 10.2210/pdb7txh/pdb
• Descriptor: Ras-related protein M-Ras, Leucine-rich repeat protein SHOC-2, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit, ... (9 entities in total)
• Functional Keywords: ras, pp1, shoc2, lrr, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 225667.97

Authors

Hauseman, Z.J.,Viscomi, J.,Dhembi, A.,Clark, K.,King, D.A.,Fodor, M. (deposition date: 2022-02-09, release date: 2022-06-22, Last modification date: 2023-10-18)

• Primary citation: Hauseman, Z.J.,Fodor, M.,Dhembi, A.,Viscomi, J.,Egli, D.,Bleu, M.,Katz, S.,Park, E.,Jang, D.M.,Porter, K.A.,Meili, F.,Guo, H.,Kerr, G.,Molle, S.,Velez-Vega, C.,Beyer, K.S.,Galli, G.G.,Maira, S.M.,Stams, T.,Clark, K.,Eck, M.J.,Tordella, L.,Thoma, C.R.,King, D.A.; Structure of the MRAS-SHOC2-PP1C phosphatase complex.; Nature, 609:416-423, 2022; PubMed: 35830882; DOI: 10.1038/s41586-022-05086-1

Experimental method

X-RAY DIFFRACTION (1.95 Å)