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8GRU
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BU of 8gru by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca
分子名称: CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ...
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-02
公開日2022-11-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.847 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
8GRB
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BU of 8grb by Molmil
Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3
分子名称: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isoform A of Isocitrate dehydrogenase [NAD] subunit beta
著者Sun, P, Chen, X, Ding, J.
登録日2022-09-01
公開日2022-12-07
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.848 Å)
主引用文献Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction.
J.Biol.Chem., 298, 2022
6KBU
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BU of 6kbu by Molmil
Crystal structure of yedK
分子名称: GLYCEROL, SOS response-associated protein
著者Wang, N, Bao, H, Huang, H.
登録日2019-06-26
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
8GL9
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BU of 8gl9 by Molmil
Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE
分子名称: CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
著者Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J.
登録日2023-03-21
公開日2023-07-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
8GLA
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BU of 8gla by Molmil
Co-crystal structure of caPCNA bound to the AOH1996 derivative, AOH1996-1LE
分子名称: CHLORIDE ION, N-[2-(3-methoxyphenoxy)phenyl]-N~2~-(naphthalene-1-carbonyl)-L-alpha-glutamine, Proliferating cell nuclear antigen
著者Jossart, J, Perry, J.J.
登録日2023-03-21
公開日2023-07-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献Small molecule targeting of transcription-replication conflict for selective chemotherapy.
Cell Chem Biol, 30, 2023
6KBZ
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BU of 6kbz by Molmil
Crystal structure of yedK with ssDNA containing a tetrahydrofuran abasic site
分子名称: 5'-D (*CP*GP*GP*TP* (3DR) P*GP*AP*TP*TP*C)-3', MAGNESIUM ION, SOS response-associated protein
著者Wang, N, Bao, H, Huang, H.
登録日2019-06-26
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
6KBX
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BU of 6kbx by Molmil
Crystal structure of yedK in complex with ssDNA containing abasic site
分子名称: DNA 5'-D (*CP*GP*GP*TP* (PED)P*GP*AP*TP*TP*C)-3', SOS response-associated protein
著者Wang, N, Bao, H, Huang, H.
登録日2019-06-26
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.221 Å)
主引用文献Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
6KBS
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BU of 6kbs by Molmil
Crystal structure of yedK in complex with ssDNA
分子名称: DNA (5'-D(*CP*GP*GP*TP*CP*GP*AP*TP*TP*C)-3'), SOS response-associated protein
著者Wang, N, Bao, H, Huang, H.
登録日2019-06-26
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
6KCQ
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BU of 6kcq by Molmil
Crystal structure of yedK with ssDNA containing an abasic site
分子名称: DNA (5'-D(P*AP*AP*AP*(PED)P*AP*A)-3'), SOS response-associated protein
著者Wang, N, Bao, H, Huang, H.
登録日2019-06-28
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.701 Å)
主引用文献Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
8GBN
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BU of 8gbn by Molmil
Structure of Apo Human SIRT5 P114T Mutant
分子名称: 1,2-ETHANEDIOL, NAD-dependent protein deacylase sirtuin-5, mitochondrial, ...
著者Petrunak, E.M, Stuckey, J.A.
登録日2023-02-26
公開日2024-06-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice.
Iscience, 27, 2024
8GBL
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BU of 8gbl by Molmil
Structure of Apo Human SIRT5
分子名称: NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION
著者Petrunak, E.M, Stuckey, J.A.
登録日2023-02-26
公開日2024-06-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice.
Iscience, 27, 2024
8H8X
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BU of 8h8x by Molmil
Cryo-EM structure of HACE1 monomer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J.
登録日2022-10-24
公開日2023-06-28
最終更新日2024-01-10
実験手法ELECTRON MICROSCOPY (3.92 Å)
主引用文献Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
8HAE
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BU of 8hae by Molmil
Cryo-EM structure of HACE1 dimer
分子名称: E3 ubiquitin-protein ligase HACE1
著者Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J, Machida, S.
登録日2022-10-26
公開日2023-06-28
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization.
Adv Sci, 10, 2023
6LBC
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BU of 6lbc by Molmil
shrimp ferritin-T158R
分子名称: FE (III) ION, Ferritin
著者Zhao, G, Chen, H, Zhang, T.
登録日2019-11-14
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions.
Food Chem, 349, 2021
6LBD
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BU of 6lbd by Molmil
shrimp ferritin T158R G159R
分子名称: CHLORIDE ION, FE (III) ION, Ferritin
著者Zhao, G, Chen, H.
登録日2019-11-14
公開日2020-11-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.386 Å)
主引用文献Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions.
Food Chem, 349, 2021
7XXY
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BU of 7xxy by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein with lactose
分子名称: Galectin-10/Charcot-Leyden crystal protein, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXW
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BU of 7xxw by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with glycerol
分子名称: GLYCEROL, Galectin
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXV
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BU of 7xxv by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with lactose
分子名称: Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXU
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BU of 7xxu by Molmil
Macaca fascicularis galectin-10/Charcot-Leyden crystal protein
分子名称: Galectin
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXZ
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BU of 7xxz by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein with glycerol
分子名称: GLYCEROL, Galectin-10/Charcot-Leyden crystal protein
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
7XXX
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BU of 7xxx by Molmil
Macaca mulatta galectin-10/Charcot-Leyden crystal protein
分子名称: Galectin-10/Charcot-Leyden crystal protein
著者Su, J.Y.
登録日2022-05-31
公開日2023-04-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
Acta Biochim.Biophys.Sin., 55, 2023
6KIJ
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BU of 6kij by Molmil
Crystal structure of yedK with ssDNA containing an abasic site
分子名称: DNA (5'-D(*GP*AP*TP*TP*CP*GP*TP*CP*G)-3'), GLYCEROL, PENTANE-3,4-DIOL-5-PHOSPHATE, ...
著者Wang, N, Bao, H, Huang, H.
登録日2019-07-18
公開日2019-08-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK.
Nucleic Acids Res., 47, 2019
7C7E
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BU of 7c7e by Molmil
Crystal structure of C terminal domain of Escherichia coli DgoR
分子名称: Putative DNA-binding transcriptional regulator, SULFATE ION, TRIETHYLENE GLYCOL, ...
著者Lin, W.
登録日2020-05-25
公開日2021-01-20
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket.
Front Microbiol, 11, 2020
7WZ6
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BU of 7wz6 by Molmil
Crystal structure of MyoD-E47
分子名称: Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1
著者Zhong, J, Huang, Y, Ma, J.
登録日2022-02-17
公開日2022-06-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis of the bHLH domains of MyoD-E47 heterodimer.
Biochem.Biophys.Res.Commun., 621, 2022
7CFP
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BU of 7cfp by Molmil
Crystal structure of WDR5 in complex with a H3Q5ser peptide
分子名称: H3Q5ser peptide, SEROTONIN, WD repeat-containing protein 5
著者Zhao, J, Zhang, X, Zang, J.
登録日2020-06-27
公開日2021-07-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the recognition of histone H3Q5 serotonylation by WDR5.
Sci Adv, 7, 2021

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