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8V95
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BU of 8v95 by Molmil
GII.8 Amsterdam norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein (Fragment)
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8V96
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BU of 8v96 by Molmil
GII.14 M7 norovirus protruding domain
分子名称: 1,2-ETHANEDIOL, Capsid protein VP1
著者Kher, G, Prewitt, A, Pancera, M, Hansman, G.
登録日2023-12-07
公開日2024-06-19
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses.
J.Virol., 98, 2024
8UKE
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BU of 8uke by Molmil
Crystal Structure of Norbelladine O-methyltransferase variant in complex with SAH
分子名称: CALCIUM ION, Norbelladine 4'-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kim, W, Zhang, Y.J.
登録日2023-10-12
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.
Nat Commun, 15, 2024
6VYC
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BU of 6vyc by Molmil
Crystal structure of WD-repeat domain of human WDR91
分子名称: UNKNOWN ATOM OR ION, WD repeat-containing protein 91
著者Halabelian, L, Hutchinson, A, Li, Y, Seitova, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2020-02-26
公開日2020-03-25
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning.
J.Med.Chem., 66, 2023
6VRT
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BU of 6vrt by Molmil
LT1009 humanized antibody Fab fragment in complex with calcium
分子名称: CALCIUM ION, SULFATE ION, Sonepcizumab antibody Fab fragment, ...
著者Fleming, J.K, Huxford, T.
登録日2020-02-09
公開日2020-04-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.555 Å)
主引用文献Ion binding properties of a naturally occurring metalloantibody
Antibodies, 9, 2020
2LDD
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BU of 2ldd by Molmil
Solution structure of the estrogen receptor-binding stapled peptide SP6 (Ac-EKHKILXRLLXDS-NH2)
分子名称: Estrogen receptor-binding stapled peptide SP6
著者Phillips, C, Bazin, R, Bent, A, Davies, N, Moore, R, Pannifer, A, Pickford, A, Prior, S, Read, C, Roberts, L, Schade, M, Scott, A, Brown, D, Xu, B, Irving, S.
登録日2011-05-21
公開日2011-07-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDA
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BU of 2lda by Molmil
Solution structure of the estrogen receptor-binding stapled peptide SP2 (Ac-HKXLHQXLQDS-NH2)
分子名称: Estrogen receptor-binding stapled peptide SP2
著者Phillips, C, Bazin, R, Bent, A, Davies, N, Moore, R, Pannifer, A, Pickford, A, Prior, S, Read, C, Roberts, L, Schade, M, Scott, A, Brown, D, Xu, B, Irving, S.
登録日2011-05-20
公開日2011-07-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDC
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BU of 2ldc by Molmil
Solution structure of the estrogen receptor-binding stapled peptide SP1 (Ac-HXILHXLLQDS-NH2)
分子名称: Estrogen receptor-binding stapled peptide SP1
著者Phillips, C, Bazin, R, Bent, A, Davies, N, Moore, R, Pannifer, A, Pickford, A, Prior, S, Read, C, Roberts, L, Schade, M, Scott, A, Brown, D, Xu, B, Irving, S.
登録日2011-05-20
公開日2011-07-06
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2M50
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BU of 2m50 by Molmil
Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).
分子名称: Mu-theraphotoxin-Hh2a
著者Gibbs, A, Minassian, N, Flinspach, M, Wickenden, A.
登録日2013-02-12
公開日2013-06-19
最終更新日2023-11-29
実験手法SOLUTION NMR
主引用文献Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
2MH0
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BU of 2mh0 by Molmil
Solution NMR structure of the p300 Taz2:ETAD1 complex
分子名称: Histone acetyltransferase p300, Transcription factor E2-alpha
著者Langelaan, D.N, Smith, S.P, Chitayat, S.
登録日2013-11-12
公開日2014-11-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.
J.Biol.Chem., 295, 2020
2M4X
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BU of 2m4x by Molmil
Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).
分子名称: Mu-theraphotoxin-Hh2a
著者Gibbs, A, Flinspach, M.
登録日2013-02-11
公開日2013-06-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
2M4Z
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BU of 2m4z by Molmil
Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin, Huwentoxin-IV (-TRTX-Hh2a).
分子名称: Mu-theraphotoxin-Hh2a
著者Gibbs, A.
登録日2013-02-12
公開日2013-06-19
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Analysis of the Structural and Molecular Basis of Voltage-sensitive Sodium Channel Inhibition by the Spider Toxin Huwentoxin-IV ( mu-TRTX-Hh2a).
J.Biol.Chem., 288, 2013
8ELF
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BU of 8elf by Molmil
Structure of Get3d, a homolog of Get3, from Arabidopsis thaliana
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ...
著者Manu, M.S, Barlow, A.N, Clemons Jr, W.M, Ramasamy, S.
登録日2022-09-23
公開日2023-05-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis.
J.Biol.Chem., 299, 2023
8EGK
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BU of 8egk by Molmil
Re-refinement of Crystal Structure of NosGet3d, the All4481 protein from Nostoc sp. PCC 7120
分子名称: AZIDE ION, All4481 protein
著者Barlow, A.N, Manu, M.S, Ramasamy, S, Clemons Jr, W.M.
登録日2022-09-12
公開日2023-05-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of Get3d reveal a distinct architecture associated with the emergence of photosynthesis.
J.Biol.Chem., 299, 2023
8F54
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BU of 8f54 by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_1
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F4X
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BU of 8f4x by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_1-H11
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
8F53
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BU of 8f53 by Molmil
Top-down design of protein architectures with reinforcement learning
分子名称: RC_I_2
著者Borst, A.J, Baker, D.
登録日2022-11-11
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Top-down design of protein architectures with reinforcement learning.
Science, 380, 2023
1EDV
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BU of 1edv by Molmil
SOLUTION STRUCTURE OF 2ND INTRADISKAL LOOP OF BOVINE RHODOPSIN (RESIDUES 172-205)
分子名称: RHODOPSIN
著者Yeagle, P.L, Salloum, A, Chopra, A, Bhawsar, N, Ali, L.
登録日2000-01-28
公開日2000-08-09
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structures of the intradiskal loops and amino terminus of the G-protein receptor, rhodopsin.
J.Pept.Res., 55, 2000
8EDE
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BU of 8ede by Molmil
Crystal structure of covalent inhibitor 2-chloro-N'-(N-(4-chlorophenyl)-N-methylglycyl)acetohydrazide bound to Ubiquitin C-terminal Hydrolase-L1
分子名称: 2-[(4-chlorophenyl)-methyl-amino]-~{N}'-ethanoyl-ethanehydrazide, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L1
著者Patel, R, Imhoff, R, Flaherty, D, Das, C.
登録日2022-09-04
公開日2023-09-20
最終更新日2024-04-10
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
J.Med.Chem., 67, 2024
8EEA
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BU of 8eea by Molmil
Structure of E.coli Septu (PtuAB) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA, PtuB
著者Shen, Z.F, Fu, T.M.
登録日2022-09-06
公開日2023-12-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8EE7
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BU of 8ee7 by Molmil
Structure of focused PtuA(dimer) and PtuB(monomer) complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA, PtuB
著者Shen, Z.F, Fu, T.M.
登録日2022-09-06
公開日2024-01-03
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8EE4
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BU of 8ee4 by Molmil
Structure of PtuA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, PtuA
著者Shen, Z.F, Fu, T.M.
登録日2022-09-06
公開日2024-01-03
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献PtuA and PtuB assemble into an inflammasome-like oligomer for anti-phage defense.
Nat.Struct.Mol.Biol., 31, 2024
8FMI
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BU of 8fmi by Molmil
Crystal structure of human KRAS at 1.12 A
分子名称: GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION
著者Brenner, R, Landgraf, A, Gonzalez-Gutierrez, G, Bum-Erdene, K, Meroueh, S.O.
登録日2022-12-23
公開日2023-11-29
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling.
Biochemistry, 62, 2023
8FMK
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BU of 8fmk by Molmil
Crystal structure of human KRAS with extended switch I loop
分子名称: CHLORIDE ION, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Brenner, R, Landgraf, A, Gonzalez-Gutierrez, G, Bum-Erdene, K, Meroueh, S.O.
登録日2022-12-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling.
Biochemistry, 62, 2023
8FMJ
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BU of 8fmj by Molmil
Crystal structure of human KRAS in space group R32
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Brenner, R, Landgraf, A, Gonzalez-Gutierrez, G, Bum-Erdene, K, Meroueh, S.O.
登録日2022-12-23
公開日2023-11-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Crystal Packing Reveals a Potential Autoinhibited KRAS Dimer Interface and a Strategy for Small-Molecule Inhibition of RAS Signaling.
Biochemistry, 62, 2023

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