8F4X

Top-down design of protein architectures with reinforcement learning

Summary for 8F4X

Entry DOI	10.2210/pdb8f4x/pdb
EMDB information	28858
Descriptor	RC_I_1-H11 (1 entity in total)
Functional Keywords	nanoparticle, capsid, oligomer, de novo design, rosetta, cryoem, de novo protein, reinforcement learning
Biological source	synthetic construct
Total number of polymer chains	60
Total formula weight	465897.72
Authors	Borst, A.J.,Baker, D. (deposition date: 2022-11-11, release date: 2023-05-10, Last modification date: 2024-06-19)
Primary citation	Lutz, I.D.,Wang, S.,Norn, C.,Courbet, A.,Borst, A.J.,Zhao, Y.T.,Dosey, A.,Cao, L.,Xu, J.,Leaf, E.M.,Treichel, C.,Litvicov, P.,Li, Z.,Goodson, A.D.,Rivera-Sanchez, P.,Bratovianu, A.M.,Baek, M.,King, N.P.,Ruohola-Baker, H.,Baker, D. Top-down design of protein architectures with reinforcement learning. Science, 380:266-273, 2023 Cited by PubMed: 37079676 DOI: 10.1126/science.adf6591 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.01 Å)

Structure validation