8UKE

Crystal Structure of Norbelladine O-methyltransferase variant in complex with SAH

Summary for 8UKE

• Entry DOI: 10.2210/pdb8uke/pdb
• Descriptor: Norbelladine 4'-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: methyltransferase, sah, ml-guided protein engineering, transferase
• Biological source: Narcissus aff. pseudonarcissus MK-2014
• Total number of polymer chains: 6
• Total formula weight: 166383.45

Authors

Kim, W.,Zhang, Y.J. (deposition date: 2023-10-12, release date: 2024-03-20)

• Primary citation: d'Oelsnitz, S.,Diaz, D.J.,Kim, W.,Acosta, D.J.,Dangerfield, T.L.,Schechter, M.W.,Minus, M.B.,Howard, J.R.,Do, H.,Loy, J.M.,Alper, H.S.,Zhang, Y.J.,Ellington, A.D.; Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.; Nat Commun, 15:2084-2084, 2024; PubMed: 38453941; DOI: 10.1038/s41467-024-46356-y

Experimental method

X-RAY DIFFRACTION (2.4 Å)