8IP6
 
 | | Cryo-EM structure of hMRS2-rest | | 分子名称: | CHLORIDE ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | | 登録日 | 2023-03-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel.
Nat Commun, 14, 2023
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8IP3
 | | Cryo-EM structure of hMRS2-Mg | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Magnesium transporter MRS2 homolog, ... | | 著者 | Li, M, Li, Y, Yang, X, Shen, Y.Q. | | 登録日 | 2023-03-14 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Molecular basis of Mg 2+ permeation through the human mitochondrial Mrs2 channel.
Nat Commun, 14, 2023
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5HJI
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5HJK
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5HJM
 | | Crystal Structure of Pyrococcus abyssi Trm5a complexed with MTA | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, ACETATE ION, HOMOSERINE LACTONE, ... | | 著者 | Xie, W, Wang, C, Jia, Q. | | 登録日 | 2016-01-13 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.762 Å) | | 主引用文献 | Crystal structures of the bifunctional tRNA methyltransferase Trm5a
Sci Rep, 6, 2016
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3KQI
 | | crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide | | 分子名称: | CHLORIDE ION, GLYCEROL, H3K4Me3 peptide, ... | | 著者 | Wen, H, Li, J.Z, Song, T, Lu, M, Lee, M. | | 登録日 | 2009-11-17 | | 公開日 | 2010-02-02 | | 最終更新日 | 2019-02-13 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285, 2010
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4IA0
 | | Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | | 分子名称: | 5-bromo-2-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-6-octylpyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Ren, J, Chen, T, Xu, Y. | | 登録日 | 2012-12-05 | | 公開日 | 2014-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.
Bioorg.Med.Chem.Lett., 23, 2013
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8TCF
 | | Integrin alpha-v beta-8 in complex with minibinder B8_BP_dsulf | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | | 登録日 | 2023-06-30 | | 公開日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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8TCG
 | | Integrin alpha-v beta-6 in complex with minibinder B6_BP_dslf | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Integrin alpha-V heavy chain, ... | | 著者 | Campbell, M.G, Fernandez, A, Roy, A, Kraft, J, Baker, D. | | 登録日 | 2023-06-30 | | 公開日 | 2023-09-27 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | De novo design of highly selective miniprotein inhibitors of integrins alpha v beta 6 and alpha v beta 8.
Nat Commun, 14, 2023
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8IBV
 | | Cryo-EM structure of the motilin-bound motilin receptor-Gq protein complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ... | | 著者 | Jiang, Y, Xu, H.E, You, C, Xu, Y. | | 登録日 | 2023-02-10 | | 公開日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
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8IBU
 | | Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex | | 分子名称: | ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | You, C, Jiang, Y, Xu, H.E, Xu, Y. | | 登録日 | 2023-02-10 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.51 Å) | | 主引用文献 | Structural basis for motilin and erythromycin recognition by motilin receptor.
Sci Adv, 9, 2023
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2HHN
 | | Cathepsin S in complex with non covalent arylaminoethyl amide. | | 分子名称: | Cathepsin S, N-[(1R)-1-[(BENZYLSULFONYL)METHYL]-2-{[(1S)-1-METHYL-2-{[4-(TRIFLUOROMETHOXY)PHENYL]AMINO}ETHYL]AMINO}-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE, SULFATE ION | | 著者 | Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K. | | 登録日 | 2006-06-28 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers
Bioorg.Med.Chem.Lett., 16, 2006
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7V7M
 | | crystal structure of SARS-CoV-2 3CL protease | | 分子名称: | 3C-like proteinase | | 著者 | Yi, Y, Zhang, M, Ye, M. | | 登録日 | 2021-08-21 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Schaftoside inhibits 3CL pro and PL pro of SARS-CoV-2 virus and regulates immune response and inflammation of host cells for the treatment of COVID-19.
Acta Pharm Sin B, 12, 2022
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6IVU
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6IVS
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4N0S
 | | Complex of ERK2 with caffeic acid | | 分子名称: | CAFFEIC ACID, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | | 著者 | Kurinov, I, Malakhova, M. | | 登録日 | 2013-10-02 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.7992 Å) | | 主引用文献 | Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis.
Cancer Prev Res (Phila), 7, 2014
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6O3E
 | | mouse aE-catenin 82-883 | | 分子名称: | Catenin alpha-1 | | 著者 | Pokutta, S, Weis, W.I. | | 登録日 | 2019-02-26 | | 公開日 | 2019-11-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (4.001 Å) | | 主引用文献 | Binding partner- and force-promoted changes in alpha E-catenin conformation probed by native cysteine labeling.
Sci Rep, 9, 2019
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6PUX
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8DJG
 | | ADGRL3-lectin domain in complex with an activating synthetic antibody fragment | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Isoform 2 of Adhesion G protein-coupled receptor L3, ... | | 著者 | Kordon, S.P, Bandekar, S.J, Arac, D. | | 登録日 | 2022-06-30 | | 公開日 | 2023-02-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Isoform- and ligand-specific modulation of the adhesion GPCR ADGRL3/Latrophilin3 by a synthetic binder.
Nat Commun, 14, 2023
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6J0Z
 | | Crystal structure of AlpK | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Putative angucycline-like polyketide oxygenase | | 著者 | Wang, W, Liu, Y, Liang, H. | | 登録日 | 2018-12-27 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.889 Å) | | 主引用文献 | Crystal structure of AlpK: An essential monooxygenase involved in the biosynthesis of kinamycin
Biochem. Biophys. Res. Commun., 510, 2019
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4EYA
 | | Crystal Structure of a Plectonemic RNA Supercoil | | 分子名称: | GLYCEROL, N utilization substance protein B homolog, RNA (5'-R(*GP*GP*CP*UP*CP*CP*UP*UP*GP*GP*CP*A)-3'), ... | | 著者 | Stagno, J.R, Ji, X. | | 登録日 | 2012-05-01 | | 公開日 | 2012-06-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of a plectonemic RNA supercoil.
Nat Commun, 3, 2012
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4M58
 | | Crystal Structure of an transition metal transporter | | 分子名称: | Cobalamin biosynthesis protein CbiM, NICKEL (II) ION | | 著者 | Yu, Y, Yan, C.Y, Zhang, B, Li, X.L, Gu, J.K. | | 登録日 | 2013-08-08 | | 公開日 | 2014-03-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters
Cell Res., 24, 2014
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5VEH
 | | Re-refinement OF THE PDB STRUCTURE 1yiz of Aedes aegypti kynurenine aminotransferase | | 分子名称: | BROMIDE ION, GLYCEROL, Kynurenine aminotransferase | | 著者 | Wlodawer, A, Dauter, Z, Minor, W, Stanfield, R, Porebski, P, Jaskolski, M, Pozharski, E, Weichenberger, C.X, Rupp, B. | | 登録日 | 2017-04-04 | | 公開日 | 2017-11-29 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Detect, correct, retract: How to manage incorrect structural models.
FEBS J., 285, 2018
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8EBM
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8EBN
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