3KQI

crystal structure of PHF2 PHD domain complexed with H3K4Me3 peptide

Summary for 3KQI

DescriptorPHD finger protein 2, H3K4Me3 peptide, ZINC ION, ... (7 entities in total)
Functional Keywordsphd finger, metal-binding, zinc-finger, histone-binding, nuclear protein
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight10233.44
Authors
Wen, H.,Li, J.Z.,Song, T.,Lu, M.,Lee, M. (deposition date: 2009-11-17, release date: 2010-02-02, Last modification date: 2019-02-13)
Primary citation
Wen, H.,Li, J.,Song, T.,Lu, M.,Kan, P.Y.,Lee, M.G.,Sha, B.,Shi, X.
Recognition of histone H3K4 trimethylation by the plant homeodomain of PHF2 modulates histone demethylation.
J.Biol.Chem., 285:9322-9326, 2010
PubMed: 20129925 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.C109.097667
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.78 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21830 1.5% 6.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3kqi
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Molmil generated image of 3kqi
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Molmil generated image of 3kqi
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More Biological unit images

Molmil generated image of 3kqi
no rotation
Molmil generated image of 3kqi
rotated about x axis by 90°
Molmil generated image of 3kqi
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3kqi.pdb2.gz [31.91 KB])
Coordinate files for Biological unit (3kqi.pdb1.gz [16.77 KB])
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