4N0S

Complex of ERK2 with caffeic acid

Summary for 4N0S

• Entry DOI: 10.2210/pdb4n0s/pdb
• Related: 3SA0
• Descriptor: Mitogen-activated protein kinase 1, CAFFEIC ACID, SULFATE ION, ... (6 entities in total)
• Functional Keywords: caffeic acid complex, mitogen-activated protein kinase, signal-regulated kinase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, spindle : P28482
• Total number of polymer chains: 1
• Total formula weight: 42479.86

Authors

Kurinov, I.,Malakhova, M. (deposition date: 2013-10-02, release date: 2014-08-27, Last modification date: 2023-09-20)

• Primary citation: Yang, G.,Fu, Y.,Malakhova, M.,Kurinov, I.,Zhu, F.,Yao, K.,Li, H.,Chen, H.,Li, W.,Lim, D.Y.,Sheng, Y.,Bode, A.M.,Dong, Z.,Dong, Z.; Caffeic Acid Directly Targets ERK1/2 to Attenuate Solar UV-Induced Skin Carcinogenesis.; Cancer Prev Res (Phila), 7:1056-1066, 2014; PubMed: 25104643; DOI: 10.1158/1940-6207.CAPR-14-0141

Experimental method

X-RAY DIFFRACTION (1.7992 Å)