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3SYO
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Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) in complex with sodium
分子名称: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, SODIUM ION
著者Whorton, M.R, MacKinnon, R.
登録日2011-07-18
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011
3SPJ
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BU of 3spj by Molmil
Apo inward rectifier potassium channel Kir2.2 I223L mutant
分子名称: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION
著者Hansen, S.B, Tao, X, MacKinnon, R.
登録日2011-07-01
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.307 Å)
主引用文献Structural basis of PIP(2) activation of the classical inward rectifier K(+) channel Kir2.2.
Nature, 477, 2011
3SYQ
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BU of 3syq by Molmil
Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant in complex with PIP2
分子名称: G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Whorton, M.R, MacKinnon, R.
登録日2011-07-18
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.44 Å)
主引用文献Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium.
Cell(Cambridge,Mass.), 147, 2011
3U6N
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BU of 3u6n by Molmil
Open Structure of the BK channel Gating Ring
分子名称: CALCIUM ION, High-Conductance Ca2+-Activated K+ Channel protein
著者Yuan, P, MacKinnon, R.
登録日2011-10-12
公開日2011-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Open structure of the Ca(2+) gating ring in the high-conductance Ca(2+)-activated K(+) channel.
Nature, 481, 2011
2ITC
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BU of 2itc by Molmil
Potassium Channel KcsA-Fab complex in Sodium Chloride
分子名称: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ...
著者Lockless, S.W, Zhou, M, MacKinnon, R.
登録日2006-10-19
公開日2007-05-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel.
Plos Biol., 5, 2007
2HFE
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BU of 2hfe by Molmil
Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter
分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB Heavy Chain, FAB Light Chain, ...
著者Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
登録日2006-06-23
公開日2006-09-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
2IH3
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BU of 2ih3 by Molmil
Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ...
著者Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R.
登録日2006-09-25
公開日2006-11-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation.
Science, 314, 2006
2ITD
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BU of 2itd by Molmil
Potassium Channel KcsA-Fab complex in Barium Chloride
分子名称: BARIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ...
著者Lockless, S.W, Zhou, M, MacKinnon, R.
登録日2006-10-19
公開日2007-05-15
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel.
Plos Biol., 5, 2007
2IH1
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BU of 2ih1 by Molmil
Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ...
著者Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R.
登録日2006-09-25
公開日2006-11-21
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation.
Science, 314, 2006
2H8P
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BU of 2h8p by Molmil
Structure of a K channel with an amide to ester substitution in the selectivity filter
分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ...
著者Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
登録日2006-06-07
公開日2006-09-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
2HG5
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BU of 2hg5 by Molmil
Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter
分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, CESIUM ION, FAB HEAVY CHAIN, ...
著者Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
登録日2006-06-26
公開日2006-09-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
2KYH
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BU of 2kyh by Molmil
Solution structure of the voltage-sensing domain of KvAP
分子名称: Voltage-gated potassium channel
著者Butterwick, J.A, MacKinnon, R.
登録日2010-05-26
公開日2010-09-29
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution Structure and Phospholipid Interactions of the Isolated Voltage-Sensor Domain from KvAP.
J.Mol.Biol., 403, 2010
3LUT
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BU of 3lut by Molmil
A Structural Model for the Full-length Shaker Potassium Channel Kv1.2
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ...
著者Chen, X, Ni, F, Wang, Q, Ma, J.
登録日2010-02-18
公開日2010-06-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JYC
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BU of 3jyc by Molmil
Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 Angstrom resolution
分子名称: Inward-rectifier K+ channel Kir2.2, POTASSIUM ION
著者Tao, X.
登録日2009-09-21
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution.
Science, 326, 2009
3EB3
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BU of 3eb3 by Molmil
Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone
分子名称: 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2
著者Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M.
登録日2008-08-26
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4, 2008
3EAU
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BU of 3eau by Molmil
Voltage-dependent K+ channel beta subunit in complex with cortisone
分子名称: 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2
著者Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M.
登録日2008-08-26
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4, 2008
3EB4
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BU of 3eb4 by Molmil
Voltage-dependent K+ channel beta subunit (I211R) in complex with cortisone
分子名称: 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2
著者Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M.
登録日2008-08-26
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4, 2008
1G9O
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BU of 1g9o by Molmil
FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR
分子名称: NHE-RF
著者Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A.
登録日2000-11-26
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains.
J.Mol.Biol., 308, 2001
6PIS
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BU of 6pis by Molmil
Mouse two pore domain K+ channel TRAAK (K2P4.1) - Fab complex structure
分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, POTASSIUM ION, ...
著者Brohawn, S.G.
登録日2019-06-27
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier.
Elife, 8, 2019
2FEC
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BU of 2fec by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
分子名称: Fab fragment, heavy chain, light chain, ...
著者Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
登録日2005-12-15
公開日2006-01-03
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.967 Å)
主引用文献Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FEE
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BU of 2fee by Molmil
Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr
分子名称: Fab fragment, heavy chain, light chain, ...
著者Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
登録日2005-12-15
公開日2006-01-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2FED
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BU of 2fed by Molmil
Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli
分子名称: Fab fragment, heavy chain, light chain, ...
著者Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C.
登録日2005-12-15
公開日2006-01-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.317 Å)
主引用文献Separate ion pathways in a Cl-/H+ exchanger
J.Gen.Physiol., 126, 2005
2AEM
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BU of 2aem by Molmil
Crystal Structures of the MthK RCK Domain
分子名称: Calcium-gated potassium channel mthK
著者Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y.
登録日2005-07-22
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability
J.Biol.Chem., 280, 2005
2AEJ
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Crystal Structures of the MthK RCK Domain in no Ca2+ bound form
分子名称: Calcium-gated potassium channel mthK
著者Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y.
登録日2005-07-22
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability
J.Biol.Chem., 280, 2005
1D1H
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BU of 1d1h by Molmil
SOLUTION STRUCTURE OF HANATOXIN 1
分子名称: HANATOXIN TYPE 1
著者Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I.
登録日1999-09-16
公開日2000-09-20
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins.
J.Mol.Biol., 297, 2000

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