3UM7
| |
3SYQ
| Crystal structure of the G protein-gated inward rectifier K+ channel GIRK2 (Kir3.2) R201A mutant in complex with PIP2 | 分子名称: | G protein-activated inward rectifier potassium channel 2, POTASSIUM ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Whorton, M.R, MacKinnon, R. | 登録日 | 2011-07-18 | 公開日 | 2011-10-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | 主引用文献 | Crystal Structure of the Mammalian GIRK2 K(+) Channel and Gating Regulation by G Proteins, PIP(2), and Sodium. Cell(Cambridge,Mass.), 147, 2011
|
|
3U6N
| Open Structure of the BK channel Gating Ring | 分子名称: | CALCIUM ION, High-Conductance Ca2+-Activated K+ Channel protein | 著者 | Yuan, P, MacKinnon, R. | 登録日 | 2011-10-12 | 公開日 | 2011-12-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.61 Å) | 主引用文献 | Open structure of the Ca(2+) gating ring in the high-conductance Ca(2+)-activated K(+) channel. Nature, 481, 2011
|
|
2HG5
| Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter | 分子名称: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, CESIUM ION, FAB HEAVY CHAIN, ... | 著者 | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | 登録日 | 2006-06-26 | 公開日 | 2006-09-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
|
|
2HFE
| Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter | 分子名称: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB Heavy Chain, FAB Light Chain, ... | 著者 | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | 登録日 | 2006-06-23 | 公開日 | 2006-09-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
|
|
2IH3
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | 著者 | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | 登録日 | 2006-09-25 | 公開日 | 2006-11-21 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
|
|
2ITD
| Potassium Channel KcsA-Fab complex in Barium Chloride | 分子名称: | BARIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | 著者 | Lockless, S.W, Zhou, M, MacKinnon, R. | 登録日 | 2006-10-19 | 公開日 | 2007-05-15 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
|
|
2ITC
| Potassium Channel KcsA-Fab complex in Sodium Chloride | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ... | 著者 | Lockless, S.W, Zhou, M, MacKinnon, R. | 登録日 | 2006-10-19 | 公開日 | 2007-05-15 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
|
|
2IH1
| Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation | 分子名称: | (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... | 著者 | Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. | 登録日 | 2006-09-25 | 公開日 | 2006-11-21 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
|
|
2H8P
| Structure of a K channel with an amide to ester substitution in the selectivity filter | 分子名称: | (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ... | 著者 | Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. | 登録日 | 2006-06-07 | 公開日 | 2006-09-12 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
|
|
5U6O
| |
5U76
| |
5TQQ
| |
3LUT
| A Structural Model for the Full-length Shaker Potassium Channel Kv1.2 | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 2, ... | 著者 | Chen, X, Ni, F, Wang, Q, Ma, J. | 登録日 | 2010-02-18 | 公開日 | 2010-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3EB3
| Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone | 分子名称: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2 | 著者 | Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M. | 登録日 | 2008-08-26 | 公開日 | 2008-09-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4, 2008
|
|
3EAU
| Voltage-dependent K+ channel beta subunit in complex with cortisone | 分子名称: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2 | 著者 | Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M. | 登録日 | 2008-08-26 | 公開日 | 2008-09-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4, 2008
|
|
3EB4
| Voltage-dependent K+ channel beta subunit (I211R) in complex with cortisone | 分子名称: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Voltage-gated potassium channel subunit beta-2 | 著者 | Pan, Y, Weng, J, Kabaleeswaran, V, Li, H, Cao, Y, Bhosle, R.C, Zhou, M. | 登録日 | 2008-08-26 | 公開日 | 2008-09-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4, 2008
|
|
2AEM
| Crystal Structures of the MthK RCK Domain | 分子名称: | Calcium-gated potassium channel mthK | 著者 | Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y. | 登録日 | 2005-07-22 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability J.Biol.Chem., 280, 2005
|
|
3JYC
| |
6PIS
| |
2AEJ
| Crystal Structures of the MthK RCK Domain in no Ca2+ bound form | 分子名称: | Calcium-gated potassium channel mthK | 著者 | Dong, J, Shi, N, Berke, I, Chen, L, Jiang, Y. | 登録日 | 2005-07-22 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structures of the MthK RCK Domain and the Effect of Ca2+ on Gating Ring Stability J.Biol.Chem., 280, 2005
|
|
1D1H
| SOLUTION STRUCTURE OF HANATOXIN 1 | 分子名称: | HANATOXIN TYPE 1 | 著者 | Takahashi, H, Kim, J.I, Sato, K, Swartz, K.J, Shimada, I. | 登録日 | 1999-09-16 | 公開日 | 2000-09-20 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins. J.Mol.Biol., 297, 2000
|
|
1G9O
| FIRST PDZ DOMAIN OF THE HUMAN NA+/H+ EXCHANGER REGULATORY FACTOR | 分子名称: | NHE-RF | 著者 | Karthikeyan, S, Leung, T, Birrane, G, Webster, G, Ladias, J.A.A. | 登録日 | 2000-11-26 | 公開日 | 2001-05-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of the PDZ1 domain of human Na(+)/H(+) exchanger regulatory factor provides insights into the mechanism of carboxyl-terminal leucine recognition by class I PDZ domains. J.Mol.Biol., 308, 2001
|
|
2FED
| Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli | 分子名称: | Fab fragment, heavy chain, light chain, ... | 著者 | Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. | 登録日 | 2005-12-15 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.317 Å) | 主引用文献 | Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
|
|
2FEC
| Structure of the E203Q mutant of the Cl-/H+ exchanger CLC-ec1 from E.Coli | 分子名称: | Fab fragment, heavy chain, light chain, ... | 著者 | Accardi, A, Walden, M.P, Nguitragool, W, Jayaram, H, Williams, C, Miller, C. | 登録日 | 2005-12-15 | 公開日 | 2006-01-03 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (3.967 Å) | 主引用文献 | Separate ion pathways in a Cl-/H+ exchanger J.Gen.Physiol., 126, 2005
|
|