Voltage-dependent K+ channel beta subunit (I211R) in complex with cortisone

Summary for 3EB4

Related1qrq 1exb 3EAU 3EB4
DescriptorVoltage-gated potassium channel subunit beta-2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, ... (4 entities in total)
Functional Keywordskvbeta, cortisone, interface, cytoplasm, ion transport, ionic channel, nadp, phosphoprotein, potassium, potassium transport, transport, voltage-gated channel, transport protein, oxidoreductase
Biological sourceRattus norvegicus (brown rat,rat,rats)
Cellular locationCytoplasm (Potential) P62483
Total number of polymer chains1
Total molecular weight37720.08
Pan, Y.,Weng, J.,Kabaleeswaran, V.,Li, H.,Cao, Y.,Bhosle, R.C.,Zhou, M. (deposition date: 2008-08-26, release date: 2008-09-23, Last modification date: 2011-07-13)
Primary citation
Pan, Y.,Weng, J.,Kabaleeswaran, V.,Li, H.,Cao, Y.,Bhosle, R.C.,Zhou, M.
Cortisone dissociates the Shaker family K+ channels from their beta subunits.
Nat.Chem.Biol., 4:708-714, 2008
PubMed: 18806782 (PDB entries with the same primary citation)
DOI: 10.1038/nchembio.114
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2498 0.3% 0.4% 4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-28