Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation

Summary for 5TQQ

EMDB information8435 8454
DescriptorChloride channel protein, Monoclonal antibody, Fab fragment, light chain, Monoclonal antibody, Fab fragment, heavy chain (3 entities in total)
Functional Keywordsclc, chloride channel, membrane, kidney, transport protein
Biological sourceBos taurus (Bovine)
Total number of polymer chains6
Total molecular weight195957.31
Park, E.,MacKinnon, R. (deposition date: 2016-10-24, release date: 2017-01-04, Last modification date: 2019-11-20)
Primary citation
Park, E.,Campbell, E.B.,MacKinnon, R.
Structure of a CLC chloride ion channel by cryo-electron microscopy.
Nature, 541:500-505, 2017
PubMed: 28002411 (PDB entries with the same primary citation)
DOI: 10.1038/nature20812
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers6 0.1% 0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report