5TQQ

Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Chloride channel protein	polymer	671	73521.5	2	UniProt (E1B792) Pfam (PF00654) In PDB	Bos taurus (Bovine)
2	L, M	Monoclonal antibody, Fab fragment, light chain	polymer	107	11824.1	2		Mus musculus (house mouse)
3	H, I	Monoclonal antibody, Fab fragment, heavy chain	polymer	113	12633.1	2		Mus musculus (house mouse)

Sequence modifications

A, B: 27 - 687 (UniProt: E1B792)

PDB	External Database	Details
Met 26	-	initiating methionine
Gln 373	Asn 373	engineered mutation
Ser 688	-	expression tag
Asn 689	-	expression tag
Ser 690	-	expression tag
Leu 691	-	expression tag
Glu 692	-	expression tag
Val 693	-	expression tag
Leu 694	-	expression tag
Phe 695	-	expression tag
Gln 696	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	195957.3
All*	Total formula weight	195957.3

*Water molecules are not included.