3EB3

Voltage-dependent K+ channel beta subunit (W121A) in complex with cortisone

Summary for 3EB3

Entry DOI	10.2210/pdb3eb3/pdb
Related	1exb 1qrq 3EAU 3EB4
Descriptor	Voltage-gated potassium channel subunit beta-2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, ... (4 entities in total)
Functional Keywords	kvbeta, cortisone, interface, cytoplasm, ion transport, ionic channel, nadp, phosphoprotein, potassium, potassium transport, transport, voltage-gated channel, transport protein, oxidoreductase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Cytoplasm (Potential): P62483
Total number of polymer chains	1
Total formula weight	37560.91
Authors	Pan, Y.,Weng, J.,Kabaleeswaran, V.,Li, H.,Cao, Y.,Bhosle, R.C.,Zhou, M. (deposition date: 2008-08-26, release date: 2008-09-23, Last modification date: 2023-08-30)
Primary citation	Pan, Y.,Weng, J.,Kabaleeswaran, V.,Li, H.,Cao, Y.,Bhosle, R.C.,Zhou, M. Cortisone dissociates the Shaker family K+ channels from their beta subunits. Nat.Chem.Biol., 4:708-714, 2008 Cited by PubMed: 18806782 DOI: 10.1038/nchembio.114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation