2HG5
Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter
Summary for 2HG5
Entry DOI | 10.2210/pdb2hg5/pdb |
Related | 2H8P 2HFE |
Descriptor | FAB HEAVY CHAIN, FAB LIGHT CHAIN, KCSA CHANNEL, ... (6 entities in total) |
Functional Keywords | channel, semi-synthetic, ester, membrane protein |
Biological source | Mus musculus (house mouse) More |
Cellular location | Cell membrane; Multi-pass membrane protein: 2HG5 |
Total number of polymer chains | 3 |
Total formula weight | 58463.56 |
Authors | Valiyaveetil, F.I.,MacKinnon, R.,Muir, T.W. (deposition date: 2006-06-26, release date: 2006-09-12, Last modification date: 2024-03-27) |
Primary citation | Valiyaveetil, F.I.,Sekedat, M.,Mackinnon, R.,Muir, T.W. Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128:11591-11599, 2006 Cited by PubMed: 16939283DOI: 10.1021/ja0631955 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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