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9EOE
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BU of 9eoe by Molmil
TF type tau filament from V337M mutant
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Qi, C, Scheres, S.H.W, Michel, G.
登録日2024-03-14
公開日2024-07-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W.
Biorxiv, 2024
6SRS
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BU of 6srs by Molmil
Structure of the Fanconi anaemia core subcomplex
分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ...
著者Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
登録日2019-09-05
公開日2019-11-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6SRI
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BU of 6sri by Molmil
Structure of the Fanconi anaemia core complex
分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ...
著者Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A.
登録日2019-09-05
公開日2019-11-06
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structure of the Fanconi anaemia monoubiquitin ligase complex.
Nature, 575, 2019
6TJO
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BU of 6tjo by Molmil
Cryo-EM structure of TypeI tau filaments extracted from the brains of individuals with Corticobasal degeneration
分子名称: Microtubule-associated protein tau
著者Zhang, W, Murzin, A.G, Falcon, B, Shi, Y, Goedert, M, Scheres, S.H.W.
登録日2019-11-26
公開日2020-02-05
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Novel tau filament fold in corticobasal degeneration.
Nature, 580, 2020
6XYO
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BU of 6xyo by Molmil
Multiple system atrophy Type I alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYP
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BU of 6xyp by Molmil
Multiple system atrophy Type II-1 alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYQ
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BU of 6xyq by Molmil
Multiple system atrophy Type II-2 alpha-synuclein filament
分子名称: Alpha-synuclein
著者Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
登録日2020-01-30
公開日2020-02-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6HRE
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Paired helical filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6HRF
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BU of 6hrf by Molmil
Straight filament from sporadic Alzheimer's disease brain
分子名称: Microtubule-associated protein tau
著者Falcon, B, Zhang, W, Schweighauser, M, Murzin, A.G, Vidal, R, Garringer, H.J, Ghetti, B, Scheres, S.H.W, Goedert, M.
登録日2018-09-26
公開日2018-10-10
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
5N9Y
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BU of 5n9y by Molmil
The full-length structure of ZntB
分子名称: Zinc transport protein ZntB
著者Cornelius, G, Stetsenko, A, Scheres, S.H.W, Slotboom, D.J, Guskov, A.
登録日2017-02-27
公開日2017-11-15
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献The structural basis of proton driven zinc transport by ZntB.
Nat Commun, 8, 2017
5NIK
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BU of 5nik by Molmil
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump
分子名称: Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC
著者Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D.
登録日2017-03-24
公開日2017-05-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
5NIL
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BU of 5nil by Molmil
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump-MacB section
分子名称: Macrolide export ATP-binding/permease protein MacB, Macrolide export protein MacA, Outer membrane protein TolC
著者Fitzpatrick, A.W.P, Llabres, S, Neuberger, A, Blaza, J.N, Bai, X.-C, Okada, U, Murakami, S, van Veen, H.W, Zachariae, U, Scheres, S.H.W, Luisi, B.F, Du, D.
登録日2017-03-24
公開日2017-05-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.3 Å)
主引用文献Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.
Nat Microbiol, 2, 2017
7ARE
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BU of 7are by Molmil
DNA origami pointer object v2
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Thomas, M, Feigl, E, Kohler, F, Kube, M, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-24
公開日2020-11-18
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7AS5
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BU of 7as5 by Molmil
126 helix bundle DNA nanostructure
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-27
公開日2020-11-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (9.8 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ART
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BU of 7art by Molmil
48 helix bundle DNA origami brick
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Feigl, E, Kube, M, Kohler, F, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-26
公開日2020-11-11
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ARV
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BU of 7arv by Molmil
TwistTower_native-twist
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-26
公開日2020-11-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
7ARY
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BU of 7ary by Molmil
Twist-Tower_twist-corrected-variant
分子名称: SCAFFOLD STRAND, STAPLE STRAND
著者Kube, M, Kohler, F, Feigl, E, Nagel-Yuksel, B, Willner, E.M, Funke, J.J, Gerling, T, Stommer, P, Honemann, M.N, Martin, T.G, Scheres, S.H.W, Dietz, H.
登録日2020-10-26
公開日2020-11-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (8.5 Å)
主引用文献Revealing the structures of megadalton-scale DNA complexes with nucleotide resolution.
Nat Commun, 11, 2020
6ZP0
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BU of 6zp0 by Molmil
Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-08
公開日2020-07-22
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZWV
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BU of 6zwv by Molmil
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: 3 Closed RBDs
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Ke, Z, Qu, K, Nakane, T, Xiong, X, Cortese, M, Zila, V, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-28
公開日2020-08-05
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures and distributions of SARS-CoV-2 spike proteins on intact virions.
Nature, 588, 2020
6ZOY
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BU of 6zoy by Molmil
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-08
公開日2020-07-22
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
7A4M
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BU of 7a4m by Molmil
Cryo-EM structure of mouse heavy-chain apoferritin at 1.22 A
分子名称: FE (III) ION, Ferritin heavy chain, ZINC ION
著者Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
登録日2020-08-20
公開日2020-10-28
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (1.22 Å)
主引用文献Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
7A5V
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BU of 7a5v by Molmil
CryoEM structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer, in complex with histamine and megabody Mb25 in lipid nanodisc
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Nakane, T, Kotecha, A, Sente, A, Yamashita, K, McMullan, G, Masiulis, S, Brown, P.M.G.E, Grigoras, I.T, Malinauskaite, L, Malinauskas, T, Miehling, J, Yu, L, Karia, D, Pechnikova, E.V, de Jong, E, Keizer, J, Bischoff, M, McCormack, J, Tiemeijer, P, Hardwick, S.W, Chirgadze, D.Y, Murshudov, G, Aricescu, A.R, Scheres, S.H.W.
登録日2020-08-22
公開日2020-11-18
最終更新日2020-11-25
実験手法ELECTRON MICROSCOPY (1.7 Å)
主引用文献Single-particle cryo-EM at atomic resolution.
Nature, 587, 2020
6ZOX
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BU of 6zox by Molmil
Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x2 disulphide-bond mutant, G413C, V987C, single Arg S1/S2 cleavage site)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-08
公開日2020-07-22
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZP2
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BU of 6zp2 by Molmil
Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Locked State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ...
著者Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-08
公開日2020-07-22
最終更新日2022-03-02
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
6ZP1
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Structure of SARS-CoV-2 Spike Protein Trimer (K986P, V987P, single Arg S1/S2 cleavage site) in Closed State
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G.
登録日2020-07-08
公開日2020-07-22
最終更新日2021-06-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020

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