5ERY
| Crystal Structure of APO MenD from M. tuberculosis - P212121 | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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2BPQ
| Anthranilate phosphoribosyltransferase (TrpD) from Mycobacterium tuberculosis (Apo structure) | 分子名称: | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, BENZAMIDINE, GLYCEROL | 著者 | Lee, C.E, Goodfellow, C, Javid-Majd, F, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2005-04-22 | 公開日 | 2006-01-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Crystal Structure of Trpd, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium Tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate J.Mol.Biol., 355, 2006
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2O7U
| Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | 著者 | Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N. | 登録日 | 2006-12-11 | 公開日 | 2007-01-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin. Acta Crystallogr.,Sect.D, 63, 2007
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2O7R
| Plant carboxylesterase AeCXE1 from Actinidia eriantha with acyl adduct | 分子名称: | CXE carboxylesterase, PROPYL ACETATE | 著者 | Ileperuma, N.R, Marshall, S.D, Squire, C.J, Baker, H.M, Oakeshott, J.G, Russell, R.J, Plummer, K.M, Newcomb, R.D, Baker, E.N. | 登録日 | 2006-12-11 | 公開日 | 2007-02-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon. Biochemistry, 46, 2007
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5ERX
| Crystal Structure of APO MenD from M. tuberculosis - I222 | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5CWA
| Structure of Anthranilate Synthase Component I (TrpE) from Mycobacterium tuberculosis with inhibitor bound | 分子名称: | 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, Anthranilate synthase component 1, GLYCEROL, ... | 著者 | Johnston, J.M, Bashiri, G, Evans, G.L, Lott, J.S, Baker, E.N. | 登録日 | 2015-07-28 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex. Acta Crystallogr.,Sect.D, 71, 2015
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5ESD
| Crystal Structure of M. tuberculosis MenD bound to ThDP and Mn2+ | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, MANGANESE (II) ION, THIAMINE DIPHOSPHATE | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESO
| Crystal Structure of M. tuberculosis MenD with ThDP, Mg2+ and Isochorismate bound | 分子名称: | (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, BETA-MERCAPTOETHANOL, ... | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-16 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESS
| Crystal Structure of M. tuberculosis MenD bound to Mg2+ and covalent intermediate I (a ThDP and decarboxylated 2-oxoglutarate adduct) | 分子名称: | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, 4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3 -ium-2-yl]-4-oxidanyl-butanoic acid, ACETATE ION, ... | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-17 | 公開日 | 2016-06-22 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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5ESU
| Crystal Structure of M. tuberculosis MenD bound to Mg2+ and Covalent Intermediate II (a ThDP + de-carboxylated 2-oxoglutarate + Isochorismate adduct) | 分子名称: | (1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, BETA-MERCAPTOETHANOL, ... | 著者 | Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N. | 登録日 | 2015-11-17 | 公開日 | 2016-06-22 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms. Structure, 24, 2016
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2O7V
| Carboxylesterase AeCXE1 from Actinidia eriantha covalently inhibited by paraoxon | 分子名称: | CXE carboxylesterase, DIETHYL PHOSPHONATE | 著者 | Ileperuma, N.R, Marshall, S.D, Squire, C.J, Baker, H.M, Oakeshott, J.G, Russell, R.J, Plummer, K.M, Newcomb, R.D, Baker, E.N. | 登録日 | 2006-12-11 | 公開日 | 2007-02-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | High-Resolution Crystal Structure of Plant Carboxylesterase AeCXE1, from Actinidia eriantha, and Its Complex with a High-Affinity Inhibitor Paraoxon. Biochemistry, 46, 2007
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2FE1
| Crystal Structure of PAE0151 from Pyrobaculum aerophilum | 分子名称: | CALCIUM ION, CHLORIDE ION, MANGANESE (II) ION, ... | 著者 | Bunker, R.D, Baker, E.N, Arcus, V.L. | 登録日 | 2005-12-15 | 公開日 | 2005-12-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operon. Proteins, 72, 2008
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1IX9
| Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution. | 分子名称: | MANGANESE (II) ION, Superoxide Dismutase | 著者 | Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B. | 登録日 | 2002-06-17 | 公開日 | 2002-12-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli To be Published
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1HSE
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1IXB
| CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION. | 分子名称: | MANGANESE ION, 1 HYDROXYL COORDINATED, SUPEROXIDE DISMUTASE | 著者 | Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B. | 登録日 | 2002-06-18 | 公開日 | 2002-12-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli To be Published
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3VEH
| Structure of a M. tuberculosis salicylate synthase, MbtI, in complex with an inhibitor methylAMT | 分子名称: | 3-{[(1Z)-1-carboxyprop-1-en-1-yl]oxy}-2-hydroxybenzoic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Bulloch, E.M, Chi, G, Manos-Turvey, A, Johnston, J.M, Baker, E.N, Payne, R.J, Lott, J.S, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-01-08 | 公開日 | 2012-06-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis. Biochemistry, 51, 2012
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4CEV
| ARGINASE FROM BACILLUS CALDEVELOX, L-ORNITHINE COMPLEX | 分子名称: | GUANIDINE, L-ornithine, MANGANESE (II) ION, ... | 著者 | Bewley, M.C, Jeffrey, P.D, Patchett, M.L, Kanyo, Z.F, Baker, E.N. | 登録日 | 1999-03-15 | 公開日 | 1999-04-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of Bacillus caldovelox arginase in complex with substrate and inhibitors reveal new insights into activation, inhibition and catalysis in the arginase superfamily. Structure Fold.Des., 7, 1999
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4BC5
| Crystal structure of human D-xylulokinase in complex with inhibitor 5- deoxy-5-fluoro-D-xylulose | 分子名称: | 1,2-ETHANEDIOL, 5-deoxy-5-fluoro-D-xylulose, XYLULOSE KINASE | 著者 | Bunker, R.D, Loomes, K.M, Baker, E.N. | 登録日 | 2012-10-01 | 公開日 | 2012-11-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4BC4
| Crystal structure of human D-xylulokinase in complex with D-xylulose | 分子名称: | 1,2-ETHANEDIOL, D-XYLULOSE, XYLULOSE KINASE | 著者 | Bunker, R.D, Loomes, K.M, Baker, E.N. | 登録日 | 2012-10-01 | 公開日 | 2012-11-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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2YPO
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with phenylalanine bound in only one site | 分子名称: | GLYCEROL, MANGANESE (II) ION, PHENYLALANINE, ... | 著者 | Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J. | 登録日 | 2012-10-31 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425, 2013
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3ZZM
| Crystal structure of Mycobacterium tuberculosis PurH with a novel bound nucleotide CFAIR, at 2.2 A resolution. | 分子名称: | 5-(FORMYLAMINO)-1-(5-O-PHOSPHONO-BETA-D-RIBOFURANOSYL)-1H-IMIDAZOLE-4-CARBOXYLIC ACID, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, GLYCEROL, ... | 著者 | Le Nours, J, Bulloch, E.M.M, Zhang, Z, Greenwood, D.R, Middleditch, M.J, Dickson, J.M.J, Baker, E.N. | 登録日 | 2011-09-02 | 公開日 | 2011-09-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Analyses of a Purine Biosynthetic Enzyme from Mycobacterium Tuberculosis Reveal a Novel Bound Nucleotide. J.Biol.Chem., 286, 2011
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4BC2
| Crystal structure of human D-xylulokinase in complex with D-xylulose and adenosine diphosphate | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, D-XYLULOSE, ... | 著者 | Bunker, R.D, Loomes, K.M, Baker, E.N. | 登録日 | 2012-10-01 | 公開日 | 2012-11-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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4BC3
| Crystal structure of human D-xylulokinase | 分子名称: | 1,2-ETHANEDIOL, XYLULOSE KINASE | 著者 | Bunker, R.D, Loomes, K.M, Baker, E.N. | 登録日 | 2012-10-01 | 公開日 | 2012-11-28 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism J.Biol.Chem., 288, 2013
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2YPQ
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with tryptophan and tyrosine bound | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J. | 登録日 | 2012-10-31 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425, 2013
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2YPP
| 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase in complex with 3 tyrosine molecules | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Blackmore, N.J, Reichau, S, Jiao, W, Hutton, R.D, Baker, E.N, Jameson, G.B, Parker, E.J. | 登録日 | 2012-10-31 | 公開日 | 2013-01-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425, 2013
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