4BC5

Crystal structure of human D-xylulokinase in complex with inhibitor 5- deoxy-5-fluoro-D-xylulose

Summary for 4BC5

• Entry DOI: 10.2210/pdb4bc5/pdb
• Related: 4B6T 4B6Y 4BC2 4BC3 4BC4
• Descriptor: XYLULOSE KINASE, 5-deoxy-5-fluoro-D-xylulose, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: transferase, glucuronate xylulokinase pathway, fggy carbohydrate kinase, inhibitor
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 3
• Total formula weight: 176216.57

Authors

Bunker, R.D.,Loomes, K.M.,Baker, E.N. (deposition date: 2012-10-01, release date: 2012-11-28, Last modification date: 2013-01-30)

• Primary citation: Bunker, R.D.,Bulloch, E.M.M.,Dickson, J.M.J.,Loomes, K.M.,Baker, E.N.; Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism; J.Biol.Chem., 288:1643-, 2013; PubMed: 23179721; DOI: 10.1074/JBC.M112.427997

Experimental method

X-RAY DIFFRACTION (1.98 Å)