2YPO

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase with phenylalanine bound in only one site

Summary for 2YPO

Entry DOI	10.2210/pdb2ypo/pdb
Related	2YPP 2YPQ
Descriptor	PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE AROG, MANGANESE (II) ION, SULFATE ION, ... (6 entities in total)
Functional Keywords	shikimate pathway, transferase, aromatic amino acid biosynth allostery
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	2
Total formula weight	102873.67
Authors	Blackmore, N.J.,Reichau, S.,Jiao, W.,Hutton, R.D.,Baker, E.N.,Jameson, G.B.,Parker, E.J. (deposition date: 2012-10-31, release date: 2013-01-09, Last modification date: 2023-12-20)
Primary citation	Blackmore, N.J.,Reichau, S.,Jiao, W.,Hutton, R.D.,Baker, E.N.,Jameson, G.B.,Parker, E.J. Three Sites and You are Out: Ternary Synergistic Allostery Controls Aromatic Aminoacid Biosynthesis in Mycobacterium Tuberculosis. J.Mol.Biol., 425:1582-, 2013 Cited by PubMed: 23274137 DOI: 10.1016/J.JMB.2012.12.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation