5CWA
Structure of Anthranilate Synthase Component I (TrpE) from Mycobacterium tuberculosis with inhibitor bound
Replaces: 4PENSummary for 5CWA
| Entry DOI | 10.2210/pdb5cwa/pdb |
| Descriptor | Anthranilate synthase component 1, SULFATE ION, GLYCEROL, ... (6 entities in total) |
| Functional Keywords | lyase, inhibitor, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
| Biological source | Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) |
| Total number of polymer chains | 1 |
| Total formula weight | 56110.76 |
| Authors | Johnston, J.M.,Bashiri, G.,Evans, G.L.,Lott, J.S.,Baker, E.N. (deposition date: 2015-07-28, release date: 2015-08-12, Last modification date: 2023-09-27) |
| Primary citation | Bashiri, G.,Johnston, J.M.,Evans, G.L.,Bulloch, E.M.,Goldstone, D.C.,Jirgis, E.N.,Kleinboelting, S.,Castell, A.,Ramsay, R.J.,Manos-Turvey, A.,Payne, R.J.,Lott, J.S.,Baker, E.N. Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex. Acta Crystallogr.,Sect.D, 71:2297-2308, 2015 Cited by PubMed: 26527146DOI: 10.1107/S1399004715017216 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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