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8DNU
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BU of 8dnu by Molmil
Human Brain Glutamine Synthetase
分子名称: Glutamine synthetase, MANGANESE (II) ION
著者Tringides, M.L.
登録日2022-07-11
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
8DNO
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BU of 8dno by Molmil
Human Brain Aldehyde Dehydrogenase 1 family, member A1
分子名称: Retinal dehydrogenase 1
著者Tringides, M.L.
登録日2022-07-11
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
8DNS
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BU of 8dns by Molmil
Human Brain Glyceraldehyde 3-phosphate dehydrogenase
分子名称: Glyceraldehyde-3-phosphate dehydrogenase
著者Tringides, M.L.
登録日2022-07-11
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
8DNM
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BU of 8dnm by Molmil
Human Brain Dihydropyrimidinase-related protein 2
分子名称: Dihydropyrimidinase-related protein 2
著者Tringides, M.L.
登録日2022-07-11
公開日2022-11-16
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献A cryo-electron microscopic approach to elucidate protein structures from human brain microsomes.
Life Sci Alliance, 6, 2023
8DYA
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BU of 8dya by Molmil
Structure of the SARS-CoV-2 spike glycoprotein S2 subunit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
登録日2022-08-03
公開日2022-11-30
最終更新日2023-01-11
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.
Sci Immunol, 7, 2022
3R24
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BU of 3r24 by Molmil
Crystal structure of nsp10/nsp16 complex of SARS coronavirus
分子名称: 2'-O-methyl transferase, Non-structural protein 10 and Non-structural protein 11, S-ADENOSYLMETHIONINE, ...
著者Liu, X, Guo, D, Su, C, Chen, Y.
登録日2011-03-13
公開日2011-10-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex.
Plos Pathog., 7, 2011
3JVH
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BU of 3jvh by Molmil
Crystal structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 8395
分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5-[(pyridin-3-ylmethyl)amino]-1H-pyrazole-4-carboxamide, GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-09-16
公開日2009-09-29
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.
J Struct Funct Genomics, 12, 2011
8DMH
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BU of 8dmh by Molmil
Lymphocytic choriomeningitis virus glycoprotein in complex with neutralizing antibody M28
分子名称: 18.5C-M28 Fab Heavy Chain, 18.5C-M28 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus.
Cell Chem Biol, 30, 2023
8DMI
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BU of 8dmi by Molmil
Lymphocytic choriomeningitis virus glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein G1, ...
著者Moon-Walker, A, Hastie, K.M, Zyla, D.S, Saphire, E.O.
登録日2022-07-08
公開日2023-04-12
最終更新日2023-05-03
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structural basis for antibody-mediated neutralization of lymphocytic choriomeningitis virus.
Cell Chem Biol, 30, 2023
8DSV
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BU of 8dsv by Molmil
The structure of NicA2 in complex with N-methylmyosmine
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FAD-dependent oxidoreductase, ...
著者Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A.
登録日2022-07-22
公開日2023-07-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.
Nat.Chem.Biol., 19, 2023
8DQ7
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BU of 8dq7 by Molmil
The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S from Pseudomonas putida
分子名称: Amine oxidase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
著者Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A.
登録日2022-07-18
公開日2023-07-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.
Nat.Chem.Biol., 2023
8DQ8
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BU of 8dq8 by Molmil
The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S in complex with N-methylmyosmine
分子名称: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 1,2-ETHANEDIOL, Amine oxidase, ...
著者Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A.
登録日2022-07-18
公開日2023-07-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.
Nat.Chem.Biol., 19, 2023
8EKY
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BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
分子名称: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EKW
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BU of 8ekw by Molmil
Cryo-EM structure of human PRDX4
分子名称: Peroxiredoxin-4
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EM2
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BU of 8em2 by Molmil
Cryo-EM structure of the human GDH/6PGL endoplasmic bifunctional protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GDH/6PGL endoplasmic bifunctional protein
著者Su, C.C.
登録日2022-09-26
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
7EAM
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BU of 7eam by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
著者Li, T.T, Gu, Y, Li, S.W.
登録日2021-03-07
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
3L72
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BU of 3l72 by Molmil
Chicken cytochrome BC1 complex with kresoxim-I-dimethyl bound
分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, CYTOCHROME B, ...
著者Huang, L, Zhang, Z, Berry, E.A.
登録日2009-12-27
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Famoxadone and related inhibitors bind like methoxy acrylate inhibitors in the Qo site of the BC1 compl and fix the rieske iron-sulfur protein in a positio close to but distinct from that seen with stigmatellin and other "DISTAL" Qo inhibitors.
To be Published
7EAN
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BU of 7ean by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ...
著者Li, T.T, Gu, Y, Li, S.W.
登録日2021-03-07
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
6LGW
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BU of 6lgw by Molmil
Structure of Rabies virus glycoprotein in complex with neutralizing antibody 523-11 at acidic pH
分子名称: Glycoprotein, scFv 523-11
著者Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W.
登録日2019-12-06
公開日2020-02-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9037 Å)
主引用文献Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
6LGX
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BU of 6lgx by Molmil
Structure of Rabies virus glycoprotein at basic pH
分子名称: Glycoprotein,Glycoprotein,Glycoprotein
著者Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W.
登録日2019-12-06
公開日2020-02-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody.
Cell Host Microbe, 27, 2020
8J30
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BU of 8j30 by Molmil
Crystal structure of ApNGT with Q469A and M218A mutations in complex with UDP-GLC
分子名称: UDP-glucose:protein N-beta-glucosyltransferase, URIDINE-5'-DIPHOSPHATE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
著者Feng, Y, Hao, Z, Guo, Q, Zheng, J, Da, L, Peng, W.
登録日2023-04-15
公開日2023-08-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Investigation of the Catalytic Mechanism of a Soluble N-glycosyltransferase Allows Synthesis of N-glycans at Noncanonical Sequons.
Jacs Au, 3, 2023
6VFE
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BU of 6vfe by Molmil
Gasdermin D pore
分子名称: Gasdermin-D, N-terminal
著者Xia, S, Ruan, J, Wu, H.
登録日2020-01-03
公開日2021-04-21
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Gasdermin D pore structure reveals preferential release of mature interleukin-1.
Nature, 593, 2021
8KHU
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BU of 8khu by Molmil
Hepatitis B virus core protein Y132A mutant in complex with THPP derivatives 48
分子名称: (6~{S},7~{R})-6,7-dimethyl-3-(2-oxidanylidenepyrrolidin-1-yl)-~{N}-[3,4,5-tris(fluoranyl)phenyl]-6,7-dihydro-4~{H}-pyrazolo[1,5-a]pyrazine-5-carboxamide, Capsid protein, GLYCEROL, ...
著者Zhou, Z, Xu, Z.H.
登録日2023-08-22
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of 4,5,6,7-Tetrahydropyrazolo[1.5-a]pyrizine Derivatives as Core Protein Allosteric Modulators (CpAMs) for the Inhibition of Hepatitis B Virus.
J.Med.Chem., 66, 2023
5V49
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BU of 5v49 by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor (Chem 1917)
分子名称: GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ...
著者Barros-Alvarez, X, Hol, W.G.J.
登録日2017-03-08
公開日2017-07-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Optimization of a binding fragment targeting the "enlarged methionine pocket" leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
6WIL
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BU of 6wil by Molmil
CdiB from Acinetobacter baumannii
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, DI(HYDROXYETHYL)ETHER, Hemolysin activator protein CdiB, ...
著者Guerin, J, Botos, I, Buchanan, S.K.
登録日2020-04-10
公開日2020-11-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insight into toxin secretion by contact dependent growth inhibition transporters.
Elife, 9, 2020

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