8DYA

Structure of the SARS-CoV-2 spike glycoprotein S2 subunit

Summary for 8DYA

• Entry DOI: 10.2210/pdb8dya/pdb
• EMDB information: 27779
• Descriptor: Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: sars-cov-2, covid-19, spike glycoprotein, fusion protein, neutralizing antibodies, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 3
• Total formula weight: 208516.10

Authors

Park, Y.J.,Seattle Structural Genomics Center for Infectious Disease (SSGCID),Veesler, D. (deposition date: 2022-08-03, release date: 2022-11-30, Last modification date: 2023-01-11)

• Primary citation: Bowen, J.E.,Park, Y.J.,Stewart, C.,Brown, J.T.,Sharkey, W.K.,Walls, A.C.,Joshi, A.,Sprouse, K.R.,McCallum, M.,Tortorici, M.A.,Franko, N.M.,Logue, J.K.,Mazzitelli, I.G.,Nguyen, A.W.,Silva, R.P.,Huang, Y.,Low, J.S.,Jerak, J.,Tiles, S.W.,Ahmed, K.,Shariq, A.,Dan, J.M.,Zhang, Z.,Weiskopf, D.,Sette, A.,Snell, G.,Posavad, C.M.,Iqbal, N.T.,Geffner, J.,Bandera, A.,Gori, A.,Sallusto, F.,Maynard, J.A.,Crotty, S.,Van Voorhis, W.C.,Simmerling, C.,Grifantini, R.,Chu, H.Y.,Corti, D.,Veesler, D.; SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.; Sci Immunol, 7:eadf1421-eadf1421, 2022; PubMed: 36356052; DOI: 10.1126/sciimmunol.adf1421

Experimental method

ELECTRON MICROSCOPY (3.67 Å)